Abate Danilo, Giusti Giuseppe, Caria Nicola, De Vita Giuseppe, Lucci Chiarissi Marco, De Lisa Antonello
Clinica Urologica, Università degli Studi di Cagliari, Ospedale SS. Trinità, Cagliari.
Arch Ital Urol Androl. 2018 Jun 30;90(2):141-142. doi: 10.4081/aiua.2018.2.141.
To describe our experience in diagnosis and treatment of urethral carcinoma following urethroplasty with a Orandi penile skin flap.
Our patient underwent to Orandi penile skin flap urethroplasty then developed a urethral epidermoid carcinoma on the flap approximately 15 years later. We treated this case with a partial penectomy surgery and perineostomy. Surgery was followed by chemotherapy with cisplatin and 5-fluorouracil. The progression of the disease led to a salvage surgery of total penectomy and asportation of testicles and scrotum.
Despite the success of the surgery, the disease progressed and three months after the last surgical operation the patient died.
Urethral carcinoma on skin flap is a rare complication of the urethroplasty surgery but with severe consequences, so we recommend to undertake a long-term urological follow up in patients undergone such kind of surgery.
描述我们使用奥兰德阴茎皮瓣行尿道成形术后诊断和治疗尿道癌的经验。
我们的患者接受了奥兰德阴茎皮瓣尿道成形术，大约15年后在皮瓣上发生了尿道表皮样癌。我们采用部分阴茎切除术和会阴造口术治疗该病例。手术后采用顺铂和5-氟尿嘧啶进行化疗。疾病进展导致了全阴茎切除术及睾丸和阴囊切除的挽救性手术。
尽管手术成功，但疾病仍进展，最后一次手术后三个月患者死亡。
皮瓣上的尿道癌是尿道成形术手术的一种罕见并发症，但后果严重，因此我们建议对接受此类手术的患者进行长期的泌尿外科随访。
