Ohta M
Gan No Rinsho. 1985 Jul;31(9 Suppl):1146-52.
In our hospital 94 patients with small cell lung cancer were admitted the past 10 years. 21 patient have undergone surgical resection following the chemotherapy with VEMT regimen. The 5 year survival rate of the patients after resection was 32.7%. The MST for 52 non-surgical patient received VEMT regimen was 8 M, but MST for the recent 15 patients received CAV or COMP regimens is prolonged by 17 M. On the treatment for non-small cell lung cancer, our recent study shows a significant improvement in response rates for patients on platinum-containing combination chemotherapy. CAP regimen produces a longer MST in patients with adenocarcinoma or large cell carcinoma compared with MFC regimen (13 M vs 9 M).
在过去10年中,我院收治了94例小细胞肺癌患者。21例患者在接受VEMT方案化疗后接受了手术切除。切除术后患者的5年生存率为32.7%。接受VEMT方案的52例非手术患者的中位生存期为8个月,但最近15例接受CAV或COMP方案的患者的中位生存期延长了17个月。在非小细胞肺癌的治疗方面,我们最近的研究表明,含铂联合化疗患者的缓解率有显著提高。与MFC方案相比,CAP方案在腺癌或大细胞癌患者中产生更长的中位生存期(13个月对9个月)。