Cremer H, Joneleit V, Seyfarth K A, Vollbrecht J D
Leber Magen Darm. 1985 Jul;15(4):148-51.
A case report is given of a 65 year old female patient harboring a rare mucoepidermoid carcinoma of the stomach. On X-ray examination a smooth faced mass with a diameter of 3 cm was found in the corpus region of the stomach. During gastroscopy the tumor was seen to be localized in the lower third of the stomach close to the lesser curvature with an ulceration on top. On microscopic examination a cornified squamous cell carcinoma was found including interspersed mucilaginous adenocarcinoma tissue. Prognosis of mucoepidermoid carcinoma is bad, histogenesis controversial. Discussion of this case as well as of other unusual adenocarcinomas for example with trophoblastic differentiation has to include the possibility of bidirectional development of undifferentiated stem cells. However it still remains unclear, why such tumors of the stomach are almost always adenocarcinomas and not signet ring cell carcinoma.
报告了一例65岁女性患者，患有罕见的胃黏液表皮样癌。X线检查发现胃体部有一个直径3cm的表面光滑的肿块。胃镜检查时，肿瘤位于胃下三分之一靠近小弯侧，顶部有溃疡。显微镜检查发现为角化鳞状细胞癌，其间散在黏液腺癌组织。黏液表皮样癌预后不良，组织发生存在争议。对该病例以及其他不寻常腺癌（例如具有滋养层分化的腺癌）的讨论必须考虑未分化干细胞双向发育的可能性。然而，胃的此类肿瘤为何几乎总是腺癌而非印戒细胞癌仍不清楚。
