Stephenson F H, Diehl W P
Mol Gen Genet. 1985;201(1):107-14. doi: 10.1007/BF00397994.
The left operator mutant lambda v2s develops poorly during infection as a result of constitutive expression of the left operon. A revertant of lambda v2s, designated lambda iri, was found to contain an inversion of the cI region with the inversion endpoints to be within the lambda operators OL and OR. Formation of the inversion is facilitated by a translocation of right operator OcR mutant sequence to the left operator in lambda v2s. The inversion in lambda iri positions wild-type OR sequence at OL returning control of the left operon to repression by the lambda cro repressor.
由于左操纵子的组成型表达，左操纵子突变体λ v2s在感染期间生长不良。发现λ v2s的一个回复体，命名为λ iri，其cI区域发生了倒位，倒位端点位于λ操纵子OL和OR内。λ v2s中右操纵子OcR突变序列向左操纵子的易位促进了倒位的形成。λ iri中的倒位将野生型OR序列置于OL处，使左操纵子的控制恢复为由λ cro阻遏物进行的阻遏。
