理解并靶向急性心肌梗死中的炎症：一个难以实现的目标。 - Suppr

Understanding and Targeting Inflammation in Acute Myocardial Infarction: An Elusive Goal.

作者信息

Granger Christopher B, Kochar Ajar

机构信息

Duke Clinical Research Institute and the Division of Cardiology, Duke University Medical Center, Durham, North Carolina.

出版信息

J Am Coll Cardiol. 2018 Jul 10;72(2):199-201. doi: 10.1016/j.jacc.2018.05.006.

DOI:10.1016/j.jacc.2018.05.006

PMID:29976294

Abstract

摘要

相似文献

Understanding and Targeting Inflammation in Acute Myocardial Infarction: An Elusive Goal.理解并靶向急性心肌梗死中的炎症：一个难以实现的目标。

J Am Coll Cardiol. 2018 Jul 10;72(2):199-201. doi: 10.1016/j.jacc.2018.05.006.

Early Use of N-acetylcysteine With Nitrate Therapy in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Segment-Elevation Myocardial Infarction Reduces Myocardial Infarct Size (the NACIAM Trial [N-acetylcysteine in Acute Myocardial Infarction]).早期使用 N-乙酰半胱氨酸联合硝酸盐治疗对行直接经皮冠状动脉介入治疗的 ST 段抬高型心肌梗死患者的心肌梗死面积的影响（NACIAM 试验[急性心肌梗死后的 N-乙酰半胱氨酸]）。

Circulation. 2017 Sep 5;136(10):894-903. doi: 10.1161/CIRCULATIONAHA.117.027575. Epub 2017 Jun 20.

Letter by Khan and Boyle Regarding Article, "Early Use of N-Acetylcysteine (NAC) With Nitrate Therapy in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction Reduces Myocardial Infarct Size (The NACIAM Trial [-Acetylcysteine in Acute Myocardial Infarction])".汗和博伊尔就文章《在接受ST段抬高型心肌梗死直接经皮冠状动脉介入治疗的患者中早期联合使用N-乙酰半胱氨酸（NAC）与硝酸盐疗法可减小心肌梗死面积（NACIAM试验 [-急性心肌梗死中的N-乙酰半胱氨酸]）》所写的信

Circulation. 2018 Mar 27;137(13):1418-1419. doi: 10.1161/CIRCULATIONAHA.117.032281.

Letter by Mansour et al Regarding Article, "Early Use of N-Acetylcysteine With Nitrate Therapy in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Segment-Elevation Myocardial Infarction Reduces Myocardial Infarct Size (the NACIAM Trial [-Acetylcysteine in Acute Myocardial Infarction])".曼苏尔等人就文章《“在接受ST段抬高型心肌梗死直接经皮冠状动脉介入治疗的患者中，早期联合使用N-乙酰半胱氨酸与硝酸盐疗法可减小心肌梗死面积（NACIAM试验[-急性心肌梗死中的N-乙酰半胱氨酸]）”》所写的信。

Circulation. 2018 Mar 27;137(13):1420-1421. doi: 10.1161/CIRCULATIONAHA.117.030180.

Letter by Ye et al Regarding Article, "Early Use of -Acetylcysteine With Nitrate Therapy in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Segment-Elevation Myocardial Infarction Reduces Myocardial Infarct Size (the NACIAM Trial [-Acetylcysteine in Acute Myocardial Infarction])".叶等人就文章《在接受ST段抬高型心肌梗死直接经皮冠状动脉介入治疗的患者中早期联合使用N-乙酰半胱氨酸和硝酸盐疗法可缩小心肌梗死面积（NACIAM试验[急性心肌梗死中的N-乙酰半胱氨酸]）》所写的信。

Circulation. 2018 Mar 27;137(13):1422-1423. doi: 10.1161/CIRCULATIONAHA.117.030312.

Response by Pasupathy et al to Letters Regarding Article, "Early Use of N-acetylcysteine (NAC) With Nitrate Therapy in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction Reduces Myocardial Infarct Size (The NACIAM Trial [-Acetylcysteine in Acute Myocardial Infarction])".帕苏帕蒂等人对关于文章《在接受ST段抬高型心肌梗死直接经皮冠状动脉介入治疗的患者中早期联合使用N-乙酰半胱氨酸（NAC）与硝酸盐疗法可减小心肌梗死面积（NACIAM试验[-急性心肌梗死中的N-乙酰半胱氨酸]）》的信件的回复

Circulation. 2018 Mar 27;137(13):1424-1425. doi: 10.1161/CIRCULATIONAHA.117.032512.

Elevated serum uric acid affects myocardial reperfusion and infarct size in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.血清尿酸水平升高会影响行直接经皮冠状动脉介入治疗的 ST 段抬高型心肌梗死患者的心肌再灌注和梗死面积。

J Cardiovasc Med (Hagerstown). 2018 May;19(5):240-246. doi: 10.2459/JCM.0000000000000634.

Letter by Rodriguez-Granillo et al Regarding Article, "Acute Myocardial Infarction: Changes in Patient Characteristics, Management, and 6-Month Outcomes Over a Period of 20 Years in the FAST-MI Program (French Registry of Acute ST-Elevation or Non-ST-Elevation Myocardial Infarction) 1995 to 2015".罗德里格斯 - 格拉尼洛等人就文章《急性心肌梗死：1995年至2015年FAST - MI项目（法国急性ST段抬高或非ST段抬高型心肌梗死注册研究）20年间患者特征、治疗及6个月预后的变化》所写的信

Circulation. 2018 May 22;137(21):2305-2306. doi: 10.1161/CIRCULATIONAHA.117.033093.

Response by Puymirat et al to Letter Regarding Article, "Acute Myocardial Infarction Changes in Patient Characteristics, Management, and 6-Month Outcomes Over a Period of 20 Years in the FAST-MI Program (French Registry of Acute ST Elevation or Non-ST-Elevation Myocardial Infarction) 1995 to 2015".皮米拉特等人对关于“1995年至2015年FAST-MI项目（法国急性ST段抬高或非ST段抬高型心肌梗死登记研究）中20年期间急性心肌梗死患者特征、管理及6个月结局变化”一文的信件的回复

Circulation. 2018 May 22;137(21):2307-2308. doi: 10.1161/CIRCULATIONAHA.118.033969.

Helicobacter pylori Seropositivity in Patients with Interleukin-1 Polymorphisms Is Significantly Associated with ST-Segment Elevation Myocardial Infarction.白细胞介素-1基因多态性患者的幽门螺杆菌血清阳性与ST段抬高型心肌梗死显著相关。

PLoS One. 2016 Nov 10;11(11):e0166240. doi: 10.1371/journal.pone.0166240. eCollection 2016.

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The associations between the FAGR and all-cause and cardiovascular mortality in patients with STEMI.ST段抬高型心肌梗死患者中FAGR与全因死亡率和心血管死亡率之间的关联。

Sci Rep. 2025 Mar 18;15(1):9237. doi: 10.1038/s41598-025-93951-0.

Soluble interleukin-2 receptor combined with interleukin-8 is a powerful predictor of future adverse cardiovascular events in patients with acute myocardial infarction.可溶性白细胞介素-2受体与白细胞介素-8联合是急性心肌梗死患者未来发生不良心血管事件的有力预测指标。

Front Cardiovasc Med. 2023 Apr 17;10:1110742. doi: 10.3389/fcvm.2023.1110742. eCollection 2023.

Prognostic Value of The Leuko-Glycemic Index in Acute Myocardial Infarction; a Systematic Review and Meta-Analysis.白细胞-血糖指数在急性心肌梗死中的预后价值；一项系统评价和荟萃分析

Arch Acad Emerg Med. 2023 Mar 1;11(1):e25. doi: 10.22037/aaem.v11i1.1915. eCollection 2023.

Prognostic Value of the Leuko-Glycemic Index in Acute Myocardial Infarction Patients with or without Diabetes.白细胞血糖指数在伴或不伴糖尿病的急性心肌梗死患者中的预后价值

Diabetes Metab Syndr Obes. 2022 Jun 9;15:1725-1736. doi: 10.2147/DMSO.S356461. eCollection 2022.

The neutrophil percentage-to-albumin ratio is associated with all-cause mortality in critically ill patients with acute myocardial infarction.中性粒细胞百分比与白蛋白比值与急性心肌梗死危重症患者的全因死亡率相关。

BMC Cardiovasc Disord. 2022 Mar 18;22(1):115. doi: 10.1186/s12872-022-02559-z.

Association of Myocardial Injury With Serum Procalcitonin Levels in Patients With ST-Elevation Myocardial Infarction.心肌损伤与 ST 段抬高型心肌梗死患者降钙素原水平的相关性。

JAMA Netw Open. 2020 Jun 1;3(6):e207030. doi: 10.1001/jamanetworkopen.2020.7030.

Cardiomyocyte microvesicles: proinflammatory mediators after myocardial ischemia?心肌细胞微囊泡：心肌缺血后的促炎介质？

J Thromb Thrombolysis. 2020 Oct;50(3):533-542. doi: 10.1007/s11239-020-02156-x.

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Understanding and Targeting Inflammation in Acute Myocardial Infarction: An Elusive Goal.

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