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精准医学在前列腺癌中的应用。

Precision medicine applications in prostate cancer.

作者信息

McCrea Edel M, Lee Daniel K, Sissung Tristan M, Figg William D

机构信息

Molecular Pharmacology Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Medical Oncology Service, and the Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

出版信息

Ther Adv Med Oncol. 2018 Jun 18;10:1758835918776920. doi: 10.1177/1758835918776920. eCollection 2018.

Abstract

Aided by developments in diagnostics and therapeutics, healthcare is increasingly moving toward precision medicine, in which treatment is customized to each individual. We discuss the relevance of precision medicine in prostate cancer, including gene targets, therapeutics and resistance mechanisms. We foresee precision medicine becoming an integral component of prostate cancer management to increase response to therapy and prolong survival.

摘要

在诊断和治疗技术发展的推动下,医疗保健正日益朝着精准医学的方向发展,即针对每个个体定制治疗方案。我们讨论了精准医学在前列腺癌中的相关性,包括基因靶点、治疗方法和耐药机制。我们预计精准医学将成为前列腺癌管理的一个不可或缺的组成部分,以提高治疗反应并延长生存期。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f0b/6024288/6ba89c8eeb2a/10.1177_1758835918776920-fig1.jpg

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