Reinhardt Florian, Mathys Britta, Reinecke Petra, Neubauer Hans, Fehm Tanja, Mohrmann Svjetlana
Department of Obstetrics and Gynecology, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Institute of Diagnostic and Interventional Radiology, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
SAGE Open Med Case Rep. 2018 Jun 12;6:2050313X18781727. doi: 10.1177/2050313X18781727. eCollection 2018.
Ductal carcinoma in situ in men is incredibly rare and detection by conventional mammography and ultrasound is often challenging. We report an unusual case of a 50-year-old male, with no family history of breast cancer, who presented with an 8-year history of left-sided breast pain and recurrent bloody nipple discharge without any significant suspicious imaging features in mammography and targeted high-resolution ultrasound. Breast magnetic resonance imaging was performed as an adjunct modality. Magnetic resonance imaging findings revealed a suspicious retroareolar non-mass abnormality of segmental, linear and dendritic pattern, which was highly suspicious for a ductal carcinoma in situ. Stereotactic guided biopsy and subsequent mastectomy were consistent with pure high-grade ductal carcinoma in situ of the left breast. Overall, this case highlights the challenges in diagnosing ductal carcinoma in situ in men and demonstrates the importance for further investigating clinical suspicions of the male breast.
男性原位导管癌极其罕见,通过传统乳腺钼靶和超声进行检测往往具有挑战性。我们报告了一例不寻常的病例,一名50岁男性,无乳腺癌家族史,有8年左侧乳房疼痛和反复乳头血性溢液病史,乳腺钼靶和靶向高分辨率超声检查均未发现任何明显可疑影像学特征。乳腺磁共振成像作为辅助检查手段进行。磁共振成像结果显示乳晕后有一个可疑的非肿块性异常,呈节段性、线性和树枝状,高度怀疑为原位导管癌。立体定向引导活检及随后的乳房切除术结果证实为左侧乳房单纯高级别原位导管癌。总体而言,该病例凸显了男性原位导管癌诊断中的挑战,并证明了对男性乳房临床可疑情况进行进一步检查的重要性。