McFarland Braxton J, Luo Alan, Wang Xiaoqin
Department of Radiology, University of Kentucky, Lexington, KY USA.
Markey Cancer Center, University of Kentucky, Lexington, KY USA.
Radiol Case Rep. 2023 Jul 17;18(9):3323-3330. doi: 10.1016/j.radcr.2023.07.001. eCollection 2023 Sep.
We report 2 rare cases of male breast cancer with bloody nipple discharge. Patient 1, a 32-year-old male, presented with a bloody nipple discharge from the left breast. Diagnostic workup revealed papillary ductal carcinoma in situ. Patient 1 underwent bilateral mastectomy with left axillary sentinel lymph node biopsy and has been doing well ever since. Patient 2, a 70-year-old male with concomitant metastatic prostate cancer, presented with a palpable right breast mass and with initially serous, then bloody nipple discharge. Diagnostic workup revealed invasive ductal carcinoma with ductal carcinoma in situ of the right breast. Patient 2 received aromatase inhibitor therapy prior to right total mastectomy with SLN biopsy followed by adjuvant tamoxifen therapy. Patient 2 recovered without complication for 2 years until metastatic disease recurrence was detected. This case report's purpose is to increase awareness and enhance understanding of the presentation, diagnosis, treatment, and outcomes of rare malignant pathologies.
我们报告2例罕见的伴有乳头血性溢液的男性乳腺癌病例。病例1为一名32岁男性，表现为左乳头血性溢液。诊断性检查发现原位乳头状导管癌。病例1接受了双侧乳房切除术及左腋窝前哨淋巴结活检，此后情况一直良好。病例2为一名70岁男性，同时患有转移性前列腺癌，表现为右乳可触及肿块，最初乳头溢液为浆液性，之后变为血性。诊断性检查发现右乳浸润性导管癌伴原位导管癌。病例2在接受右乳全切除术及前哨淋巴结活检之前接受了芳香化酶抑制剂治疗，随后接受辅助他莫昔芬治疗。病例2康复且无并发症发生，持续2年，直至检测到转移性疾病复发。本病例报告的目的是提高对罕见恶性病变的表现、诊断、治疗及预后的认识并增进理解。
