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氨氯地平所致血管性水肿：一种常见药物的不寻常并发症。

Amlodipine-induced angioedema: An unusual complication of a common medication.

作者信息

Kuruvilla Merin E, Sanan Neha

机构信息

Department of Allergy/Immunology, Emory University, Atlanta, Georgia.

Department of Internal Medicine, Saint Vincent Hospital, Worcester, Massachusetts.

出版信息

Allergy Rhinol (Providence). 2018 Apr 6;9:2152656718764139. doi: 10.1177/2152656718764139. eCollection 2018 Jan-Dec.

DOI:10.1177/2152656718764139
PMID:29977650
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6028154/
Abstract

Hypersensitivity reactions to dihydropyridine calcium channel blockers (CCB) are exceedingly rare, although sporadic reports of isolated angioedema seem to be gradually increasing in frequency. We present a case of angioedema likely triggered by amlodipine.

摘要

尽管孤立性血管性水肿的零星报告似乎在频率上逐渐增加，但对二氢吡啶类钙通道阻滞剂（CCB）的超敏反应极其罕见。我们报告一例可能由氨氯地平引发的血管性水肿病例。

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Antihypertensive drug-induced angioedema causing upper airway obstruction in children.抗高血压药物引起的血管性水肿导致儿童上呼吸道梗阻
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Angioedema associated with dihydropyridine calcium-channel blockers in a child with Burkitt lymphoma.与二氢吡啶类钙通道阻滞剂相关的血管性水肿患儿伴伯基特淋巴瘤。
Am J Health Syst Pharm. 2011 Mar 1;68(5):402-6. doi: 10.2146/ajhp100277.
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Probable amlodipine-induced angioedema.可能由氨氯地平引起的血管性水肿。
Ann Pharmacother. 2009 Apr;43(4):772-6. doi: 10.1345/aph.1L527. Epub 2009 Mar 18.
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Calcium channel blocker-associated small bowel angioedema.钙通道阻滞剂相关性小肠血管性水肿
J Clin Gastroenterol. 2009 Apr;43(4):338-41. doi: 10.1097/MCG.0b013e31815cf6b9.
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Incidence and predictors of angioedema in elderly hypertensive patients at high risk for cardiovascular disease: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).心血管疾病高危老年高血压患者血管性水肿的发生率及预测因素：抗高血压和降脂治疗预防心脏病发作试验（ALLHAT）报告
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Novel vascular biology of third-generation L-type calcium channel antagonists: ancillary actions of amlodipine.
Arterioscler Thromb Vasc Biol. 2003 Dec;23(12):2155-63. doi: 10.1161/01.ATV.0000097770.66965.2A. Epub 2003 Sep 25.
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The spectrum of cutaneous reactions associated with diltiazem: three cases and a review of the literature.与地尔硫䓬相关的皮肤反应谱：三例病例及文献综述
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Nifedipine-induced periorbital edema.硝苯地平引起的眶周水肿。
Am J Cardiol. 1985 May 1;55(11):1445. doi: 10.1016/0002-9149(85)90531-4.