Abdalla Mohammed, Sinyagovskiy Pavel, Mohamed Wiam, Abdelghani Amro
Presence St Francis Hospital, Evanston, IL, USA.
University of Khartoum, Sudan.
Respir Med Case Rep. 2018 Apr 6;24:52-54. doi: 10.1016/j.rmcr.2018.04.003. eCollection 2018.
A 58 years old male who was admitted to the intensive care unit for septic shock secondary to pneumonia, he has Crohn's disease currently treated with Vedolizumab and previously with infliximab. He was started on broad spectrum antibiotics and vasopressors for treatment of septic shock without improvement in the following days, sputum & blood cultures were negative. Bronchoscopy was done for non-resolving pneumonia work up, broncheoalveolar lavage smears and cultures were negative for bacteria, tuberculosis and Fungi. Bronchial washings cytology showed filariform larvae and serology was positive for Strongyloides, He was started on ivermectin and his condition improved significantly.
一名58岁男性因肺炎继发感染性休克入住重症监护病房,他患有克罗恩病,目前正在接受维得利珠单抗治疗,之前曾使用英夫利昔单抗治疗。他开始使用广谱抗生素和血管加压药治疗感染性休克,但在接下来的几天里病情没有改善,痰和血培养均为阴性。为明确不愈肺炎的病因进行了支气管镜检查,支气管肺泡灌洗涂片和培养未发现细菌、结核和真菌。支气管冲洗液细胞学检查显示丝状幼虫,粪类圆线虫血清学检查呈阳性,他开始接受伊维菌素治疗,病情明显改善。