在接受直接抗病毒药物（DAA）治疗后实现持续病毒学应答（SVR）的丙型肝炎病毒/艾滋病病毒（HCV/HIV）合并感染和HCV感染参与者中，HCV复发率相似：美国国立过敏与传染病研究所艾滋病临床试验组A5320病毒性丙型肝炎感染长期队列研究（V-HICS）的中期结果
Similar Low Rates of HCV Recurrence in HCV/HIV- and HCV-Infected Participants who Achieved SVR After DAA Treatment: Interim Results From the ACTG A5320 Viral Hepatitis C Infection Long-term Cohort Study (V-HICS).
作者信息
Wyles David L, Kang Minhee, Matining Roy M, Murphy Robert L, Peters Marion G
机构信息
Department of Medicine, Denver Health Medical Center, Denver, Colorado.
Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.
出版信息
Open Forum Infect Dis. 2018 Jun 4;5(6):ofy103. doi: 10.1093/ofid/ofy103. eCollection 2018 Jun.
Abstract
Hepatitis C virus (HCV) recurrence rates were similar between those with HCV/HIV co-infection (0.35/100 person-years) and HCV infection (0.42/100 person-years). Low rates of recurrence likely represent enrollment of an HIV population at low risk for recurrence. Care should be taken not to label all HCV/HIV co-infected patients as being at high risk for HCV recurrence.
摘要
丙型肝炎病毒（HCV）/人类免疫缺陷病毒（HIV）合并感染患者的丙型肝炎病毒复发率（0.35/100人年）与单纯丙型肝炎病毒感染患者（0.42/100人年）相似。复发率低可能是因为纳入了复发风险较低的HIV人群。应注意不要将所有HCV/HIV合并感染患者都标记为丙型肝炎病毒复发的高风险人群。
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