"Click" Methodology for the Functionalization of Water Oxidation Catalyst Iridium Oxide Nanoparticles with Hydrophobic Dyes for Artificial Photosynthetic Constructs.

The unusually high tolerance toward chemical functional groups of the copper(I)-catalyzed Huisgen-Sharpless-Meldal 1,3-dipolar cycloaddition of azides and alkynes protocol (the CuAAC or "click" reaction) associated with its mild conditions and high yields has been explored in the present methodology to successfully prepare water oxidation catalyst iridium oxide nanoparticles decorated with organic dyes. The "click reaction" has proven to be an excellent synthetic tool to overcome the incompatible solubility of the hydrophilic iridium oxide nanoparticles and the hydrophobic dyes. A complex artificial photosynthetic model designed to mimic the photoinduced redox processes occurring in photosystem II is used as a hydrophobic dye to highlight the efficiency and selectiveness of the method.