Andercou Octavian, Marian Dorin, Olteanu Gabriel, Stancu Bogdan, Cucuruz Beatrix, Noppeney Thomas
Second Surgical Clinic, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca Second Surgical Department, University of Medicine and Pharmacy, Targu Mures, Romania Center for Vascular Diseases and Department for Vascular Surgery Martha-Maria Hospital, Nuremberg, Germany.
Medicine (Baltimore). 2018 Jul;97(27):e11350. doi: 10.1097/MD.0000000000011350.
Infections after vascular reconstructions are very rare; however, when they occur, they are associated with a high risk of morbidity. In order to obtain the best results possible, the treatment needs to be initiated as early as possible, from the very first signs of infection, and it needs to be carried out in centers specializing in vascular surgery. The aim of the present study was to assess the incidence of infections in a single university center.This retrospective analysis over a 2-year period is based on the medical reports of hospitalized patients who were diagnosed with infection following revascularization.From 2013 to 2014, a number of 151 open reconstructive surgical procedures were performed. 15 patients suffered from infection (10%) of the vascular reconstruction. Of these patients, 40% have had an aorto-bifemoral bypass, 53%-a femoro-popliteal bypass, and 7% (n = 1)-an axillo-femoral bypass. According to the Samson classification, the patients were categorized as follows: group 2: 6 cases, group 3: 2 cases, group 4: 4 cases, and group 5: 3 cases. The most frequent bacteria found were methicillin-resistant Staphylococcus aureus (MRSA) (n = 6, 40%), followed by S aureus (n = 5, 33%). The treatment options were: application of antibiotics alone without any invasive treatment in 3 patients, local irrigation and debridement in 6 patients, complete explantation of the prosthesis with a new extra-anatomic bypass in 6 cases, and partial excision of the prosthesis, which was replaced and covered with muscle flap, in 3 cases. The amputation rate in our study was 18%, which corresponds to the rates published in the literature.The treatment of infections in vascular surgery needs to be complex and adapted to each individual patient, because infections being in a permanent dynamic state. The treatment needs to be performed in specialized centers that have large experience in vascular surgery, in order for the patient to have the best chances of survival and protection from amputation.
血管重建术后感染非常罕见;然而,一旦发生,就会伴随着高发病风险。为了尽可能获得最佳治疗效果,需要在感染的最初迹象出现时尽早开始治疗,并且要在专门的血管外科中心进行。本研究的目的是评估单一大学中心的感染发生率。这项为期2年的回顾性分析基于住院患者的医疗报告,这些患者在血管重建后被诊断出感染。2013年至2014年期间,共进行了151例开放性重建手术。15例患者发生了血管重建感染(10%)。在这些患者中,40%进行了主动脉-双股动脉旁路移植术,53%进行了股-腘动脉旁路移植术,7%(n = 1)进行了腋-股动脉旁路移植术。根据参孙分类法,患者分类如下:2组:6例,3组:2例,4组:4例,5组:3例。最常见的细菌是耐甲氧西林金黄色葡萄球菌(MRSA)(n = 6,40%),其次是金黄色葡萄球菌(n = 5,33%)。治疗方案如下:3例患者仅应用抗生素,未进行任何侵入性治疗;6例患者进行局部冲洗和清创;6例患者完全取出假体并进行新的解剖外旁路移植;3例患者部分切除假体,更换后用肌瓣覆盖。我们研究中的截肢率为18%,与文献报道的比率相符。血管外科感染的治疗需要复杂且因人而异,因为感染处于持续动态变化中。治疗需要在血管外科经验丰富的专业中心进行,以便患者有最佳的生存机会并避免截肢。