Razavi Seyed Amirhossein, Desai Karan A, Hart Alexandra M, Thompson Peter W, Losken Albert
Am Surg. 2018 Jun 1;84(6):959-962.
The goal in abdominal wall reconstruction (AWR) is to minimize morbidity and prevent hernia recurrence. Components separation and mesh reconstruction are two options, however, with advantages and disadvantages. The purpose of this review was to investigate outcomes in patients with abdominal wall hernia undergoing primary closure with component separation (CS) versus CS with acellular dermal matrix (ADM) reinforcement (CS + mesh). Medical records of consecutive patients who underwent abdominal wall reconstruction using CS with or without ADM reinforcement were retrospectively reviewed. Primary fascial closure was achieved in all patients. ADM reinforcement when used was performed using the underlay technique. Reconstructive technique and postoperative complications including delayed healing, skin necrosis, fistula, seroma, hematoma and surgical site infection, recurrence, and reoperation were recorded. Comparisons between the two groups were assessed. One hundred and seven patients were included (mean age, 55.7; 51.4% male; median follow-up 297 days). Twenty-six patients (24%) underwent CS alone; whereas 81 patients (76%) CS + mesh placement. Patient comorbidities, including smoking (26%), diabetes (20%), and hypertension (46%); body mass index (mean 32.3 ± 7.6); and albumin level on the day of surgery (mean 3.4 ± 0.5 mg/dL) were not significantly different between groups. Surgical site infection was significantly higher among CS + mesh patients (22.2%) versus CS only patients (3.9%) (P = 0.02). The recurrence rate of abdominal hernia was significantly lower in CS + mesh patients compared with CS only (14.8% vs 34.6%; P = 0.02). No significant differences in other postoperative complications were identified between the two groups. ADM reinforcement at the time of components separation is often selected in more complex, higher risk patients. Although the incidence of infection was higher in these patients, it was usually treated without mesh removal and recurrence rate was significantly lower when compared to CS alone.
腹壁重建(AWR)的目标是将发病率降至最低并防止疝复发。成分分离和补片重建是两种选择,但各有优缺点。本综述的目的是研究接受初次缝合联合成分分离(CS)与联合脱细胞真皮基质(ADM)强化的成分分离(CS + 补片)的腹壁疝患者的治疗结果。对连续接受使用CS联合或不联合ADM强化进行腹壁重建的患者的病历进行回顾性分析。所有患者均实现了筋膜初次缝合。使用ADM强化时采用的是衬里技术。记录重建技术和术后并发症,包括愈合延迟、皮肤坏死、瘘管、血清肿、血肿、手术部位感染、复发和再次手术情况。对两组之间进行比较评估。纳入了107例患者(平均年龄55.7岁;51.4%为男性;中位随访297天)。26例患者(24%)仅接受了CS;而81例患者(76%)接受了CS + 补片植入。两组患者的合并症,包括吸烟(26%)、糖尿病(20%)和高血压(46%);体重指数(平均32.3 ± 7.6);以及手术当天的白蛋白水平(平均3.4 ± 0.5 mg/dL)无显著差异。CS + 补片组患者的手术部位感染率(22.2%)显著高于仅接受CS组患者(3.9%)(P = 0.02)。与仅接受CS组相比,CS + 补片组患者的腹疝复发率显著更低(14.8%对34.6%;P = 0.02)。两组之间在其他术后并发症方面未发现显著差异。在成分分离时进行ADM强化通常在更复杂、风险更高的患者中选用。尽管这些患者的感染发生率更高,但通常无需移除补片即可治疗,且与单纯CS相比复发率显著更低。