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本文引用的文献

1
Radium-223 Therapy of Bone Metastases in Prostate Cancer.镭-223治疗前列腺癌骨转移
Semin Nucl Med. 2016 Nov;46(6):544-556. doi: 10.1053/j.semnuclmed.2016.07.007. Epub 2016 Sep 15.
2
Refractory hypocalcaemia complicating metastatic prostatic carcinoma.转移性前列腺癌并发难治性低钙血症。
BMJ Case Rep. 2015 Jun 29;2015:bcr2015210003. doi: 10.1136/bcr-2015-210003.
3
Hungry bone syndrome: persistent hypocalcemia related to osteoblastic bone metastases of prostate cancer.饥饿骨综合征:与前列腺癌成骨性骨转移相关的持续性低钙血症。
J Palliat Med. 2013 Dec;16(12):1496-7. doi: 10.1089/jpm.2013.0389. Epub 2013 Oct 26.
4
Alpha emitter radium-223 and survival in metastatic prostate cancer.α 粒子发射体镭-223 与转移性前列腺癌的生存。
N Engl J Med. 2013 Jul 18;369(3):213-23. doi: 10.1056/NEJMoa1213755.
5
Hungry bone syndrome: still a challenge in the post-operative management of primary hyperparathyroidism: a systematic review of the literature.饥饿骨综合征:原发性甲状旁腺功能亢进术后管理中的挑战仍在继续:文献系统回顾。
Eur J Endocrinol. 2013 Feb 20;168(3):R45-53. doi: 10.1530/EJE-12-0528. Print 2013 Mar.
6
Characterising the castration-resistant prostate cancer population: a systematic review.描述去势抵抗性前列腺癌人群特征:系统综述。
Int J Clin Pract. 2011 Nov;65(11):1180-92. doi: 10.1111/j.1742-1241.2011.02799.x.
7
Hypocalcemia with bony metastases in prostate cancer.前列腺癌伴骨转移的低钙血症
J Ayub Med Coll Abbottabad. 2008 Jan-Mar;20(1):138-9.
8
Severe hypocalcaemia because of osteoblastic prostate carcinoma metastases.成骨性前列腺癌转移导致的严重低钙血症。
Int J Clin Pract. 2008 Oct;62(10):1630-1. doi: 10.1111/j.1742-1241.2008.01802.x.
9
Hypocalcemia and parathyroid function in metastatic prostate cancer.转移性前列腺癌中的低钙血症与甲状旁腺功能
Endocr Pract. 2005 Jul-Aug;11(4):254-8. doi: 10.4158/EP.11.4.254.
10
Severe hypocalcaemia associated with extensive osteoblastic metastases in a patient with prostate cancer.一名前列腺癌患者出现严重低钙血症并伴有广泛成骨细胞转移。
Neth J Med. 2005 Jan;63(1):34-7.

镭疗成功治疗前列腺癌继发的饥饿骨综合征。

Hungry bone syndrome secondary to prostate cancer successfully treated with radium therapy.

作者信息

Garla Vishnu Vardhan, Salim Sohail, Kovvuru Karthik Reddy, Subauste Angela

机构信息

Department of Internal Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA.

出版信息

BMJ Case Rep. 2018 Jul 6;2018:bcr-2018-225039. doi: 10.1136/bcr-2018-225039.

DOI:10.1136/bcr-2018-225039
PMID:29982185
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6040511/
Abstract

A 50-year-old man with a history of prostate cancer with extensive bone metastasis and hypocalcaemia presented with muscle aches and cramps. Physical exam was significant for Chvostek's and Trousseau's sign. Laboratory assessment was consistent with profound hypocalcaemia. This was believed to be due to hungry bone syndrome secondary to advanced prostate cancer. He was treated with intravenous calcium, vitamin D and calcitriol. He also received three doses of radium therapy. After therapy, hypocalcaemic episodes resolved. Follow-up after 2.5 years showed continued resolution of hypocalcaemia.

摘要

一名50岁男性,有前列腺癌病史,伴有广泛骨转移和低钙血症,出现肌肉疼痛和痉挛。体格检查发现有Chvostek征和Trousseau征。实验室评估结果与严重低钙血症相符。这被认为是晚期前列腺癌继发的饥饿骨综合征所致。他接受了静脉补钙、维生素D和骨化三醇治疗。他还接受了三剂镭治疗。治疗后,低钙血症发作得到缓解。2.5年后的随访显示低钙血症持续缓解。