Lindeman P, Eggertsson S, Edström S, Aberg B
Arch Otorhinolaryngol. 1985;242(2):203-7. doi: 10.1007/BF00454422.
Forty-two patients with malignancies localized to the base of the tongue were treated at Sahlgrenska Hospital between 1971 and 1980. These patients were re-analyzed with respect to symptomatology and clinical outcome. Pain in the mouth, throat, and ears as well as swallowing difficulties were the most frequent overt symptoms of disease. In general, patients experienced symptoms for at least 3 months before a positive tumor diagnosis was made. In all, 75% of the patients were found to have large tumors which extended beyond the base of the tongue. Most of the patients were treated with irradiation. The overall 3-year survival rate was 28%, while individual patient survival was related to the size of the primary tumor and to the occurrence of lymph node metastases. Careful attention to symptomatology may reduce delays in establishing an accurate diagnosis and consequently improve the prognosis for patients with these cancers.
1971年至1980年间，索尔纳大学医院对42例舌根部局限性恶性肿瘤患者进行了治疗。对这些患者的症状学和临床结果进行了重新分析。口腔、咽喉和耳部疼痛以及吞咽困难是最常见的明显疾病症状。一般来说，患者在肿瘤确诊前至少有3个月的症状。总共发现75%的患者患有超出舌根部的大肿瘤。大多数患者接受了放射治疗。总体3年生存率为28%，而个体患者的生存与原发肿瘤的大小和淋巴结转移的发生有关。密切关注症状学可能会减少准确诊断的延迟，从而改善这些癌症患者的预后。
