Edström S, Beran M, Ejnell H, Lindström J
ORL J Otorhinolaryngol Relat Spec. 1981;43(1):50-5. doi: 10.1159/000275524.
The present investigation of a retrospective series of patients with tongue cancers aimed at assessing the results of various treatment principles. We suggest that surgery must be taken into account particularly when large primary tumors as well as palpable regional nodes are found. Because of the unpredictable metastasis behavior, even in cases of small primary tumors without clinical evidence of regional spread, the potential risk of regional microdeposits must always be suspected. Therefore, irradiation of the neck field with fractionated doses of 5,000 rad, alone or in combination with surgery should be considered in all patients with tongue cancers.
本次对一系列舌癌患者的回顾性研究旨在评估各种治疗原则的效果。我们建议，特别是在发现大的原发性肿瘤以及可触及的区域淋巴结时，必须考虑手术治疗。由于转移行为不可预测，即使在原发性肿瘤较小且无区域扩散临床证据的情况下，也必须始终怀疑存在区域微转移灶的潜在风险。因此，对于所有舌癌患者，都应考虑采用5000拉德的分次剂量对颈部区域进行放疗，可单独放疗或与手术联合放疗。
