冷暴露、甲状腺功能亢进或急性运动大鼠骨骼肌中6-磷酸果糖和1,6-二磷酸果糖之间的底物循环速率。
The rate of substrate cycling between fructose 6-phosphate and fructose 1,6-bisphosphate in skeletal muscle from cold-exposed, hyperthyroid or acutely exercised rats.
作者信息
Challis R A, Arch J R, Newsholme E A
出版信息
Biochem J. 1985 Oct 1;231(1):217-20. doi: 10.1042/bj2310217.
Abstract
The effects of cold-exposure, the hyperthyroid state and a single exercise bout in vivo on the maximal enzyme activities of 6-phosphofructokinase and fructose-1,6-bisphosphatase in vastus lateralis muscle and the rates of fructose 6-phosphate/fructose 1,6-bisphosphate cycling measured in epitrochlearis muscle in vitro were investigated. In all cases significant changes in substrate cycling rates were observed, whether in the absence of added hormones in vitro (acute exercise), or when stimulated by insulin plus adrenaline (cold-exposure), or with respect to the catecholamine-sensitivity of the cycling rate (the hyperthyroid state).
摘要
研究了冷暴露、甲状腺功能亢进状态以及单次体内运动对股外侧肌中6-磷酸果糖激酶和果糖-1,6-二磷酸酶的最大酶活性，以及体外测定的肱三头肌中6-磷酸果糖/1,6-二磷酸果糖循环速率的影响。在所有情况下，均观察到底物循环速率有显著变化，无论是在体外未添加激素的情况下（急性运动），还是在胰岛素加肾上腺素刺激下（冷暴露），或者是关于循环速率的儿茶酚胺敏感性方面（甲状腺功能亢进状态）。
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本文引用的文献
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