Greenlee Christopher J, Newton Stephen S
Department of Otolaryngology, University of Colorado School of Medicine, Aurora, Colorado, United States.
Department of Otolaryngology, Children's Hospital Colorado, Aurora, Colorado, United States.
Int Arch Otorhinolaryngol. 2018 Jul;22(3):317-329. doi: 10.1055/s-0037-1604055. Epub 2017 Jul 25.
A majority of otolaryngologists have not had direct experience with many vaccine-preventable diseases since the creation of national vaccination programs. Despite the elimination of endemic transmission of some of these diseases in the United States, outbreaks can occur anywhere and still pose a threat to public health around the world. Recent outbreaks and changing trends in exemption rates indicate that it is important for physicians to maintain a working knowledge of how these diseases present and of the recommended treatment guidelines. This review will evaluate the current state of vaccination rates, vaccine exemption rates and disease incidence in the United States and in the world. It will also examine the clinical presentation and treatment recommendations of these diseases. United States estimated vaccination rates, vaccine exemption rates and vaccine-preventable disease incidences were obtained from data compiled by the Centers for Disease Control and Prevention. World vaccination rates and disease incidences were obtained from the World Health Organization databases, which compile official figures reported by member states. A PubMed literature review provided information on the current state of vaccination exemptions and outbreaks in the United States. Vaccination and vaccine exemption rates continue to put the United States and many areas of the world at risk for outbreaks of vaccine-preventable diseases. Clinical guidelines should be reviewed in the event of a local outbreak.
自国家疫苗接种计划实施以来,大多数耳鼻喉科医生并未直接接触过许多可通过疫苗预防的疾病。尽管在美国某些此类疾病的地方性传播已被消除,但疫情仍可能在任何地方发生,并且仍然对全球公共卫生构成威胁。近期的疫情爆发以及豁免率的变化趋势表明,医生了解这些疾病的表现形式以及推荐的治疗指南非常重要。
本综述将评估美国及全球的疫苗接种率、疫苗豁免率和疾病发病率的现状。还将研究这些疾病的临床表现和治疗建议。
美国的估计疫苗接种率、疫苗豁免率和可通过疫苗预防的疾病发病率来自疾病控制与预防中心汇编的数据。全球疫苗接种率和疾病发病率来自世界卫生组织数据库,该数据库汇编了成员国报告的官方数据。通过PubMed文献综述获取了美国疫苗豁免和疫情爆发现状的信息。
疫苗接种率和疫苗豁免率继续使美国及世界许多地区面临可通过疫苗预防疾病爆发的风险。在发生局部疫情时,应审查临床指南。