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使用便携式光场眼底相机进行无眩光视网膜成像。

Glare-free retinal imaging using a portable light field fundus camera.

作者信息

Palmer Douglas W, Coppin Thomas, Rana Krishan, Dansereau Donald G, Suheimat Marwan, Maynard Michelle, Atchison David A, Roberts Jonathan, Crawford Ross, Jaiprakash Anjali

机构信息

Queensland University of Technology, Brisbane, QLD 4000, Australia.

Medical and Healthcare Robotics, Australian Centre for Robotic Vision, Brisbane, QLD 4000, Australia.

出版信息

Biomed Opt Express. 2018 Jun 20;9(7):3178-3192. doi: 10.1364/BOE.9.003178. eCollection 2018 Jul 1.

Abstract

We present the retinal plenoptoscope, a novel light field retinal imaging device designed to overcome many of the problems that limit the use of portable non-mydriatic fundus cameras, including image quality and lack of stereopsis. The design and prototype construction of this device is detailed and the ideal relationship between the eye pupil, system aperture stop and micro-image separation is investigated. A comparison of the theoretical entrance pupil size, multi-view baseline and depth resolution indicates that a higher degree of stereopsis is possible than with stereo fundus cameras. We also show that the effects of corneal backscatter on image quality can be removed through a novel method of glare identification and selective image rendering. This method is then extended to produce glare-free depth maps from densely estimated depth fields, creating representations of retinal topography from a single exposure. These methods are demonstrated on physical models and live human eyes using a prototype device based on a Lytro Illum consumer light field camera. The Retinal Plenoptoscope offers a viable, robust modality for non-mydriatic color and 3-D retinal imaging.

摘要

我们介绍了视网膜全光镜,这是一种新型的光场视网膜成像设备,旨在克服许多限制便携式免散瞳眼底相机使用的问题,包括图像质量和缺乏立体视觉。详细介绍了该设备的设计和原型构建,并研究了眼瞳孔、系统孔径光阑和微图像间距之间的理想关系。对理论入瞳尺寸、多视图基线和深度分辨率的比较表明,与立体眼底相机相比,该设备能够实现更高程度的立体视觉。我们还表明,通过一种新颖的眩光识别和选择性图像渲染方法,可以消除角膜后向散射对图像质量的影响。然后将该方法扩展,从密集估计的深度场生成无眩光深度图,通过单次曝光创建视网膜地形图。使用基于Lytro Illum消费级光场相机的原型设备,在物理模型和活体人眼上展示了这些方法。视网膜全光镜为免散瞳彩色和三维视网膜成像提供了一种可行、可靠的方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e936/6033554/584e35651882/boe-9-7-3178-g001.jpg

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