Wajih Ullah Muhammad, Amray Afshan, Qaseem Aisha, Siddiqui Tariq, Naeem Temoor
Cardiology, Mayo Clinic, Rochester, USA.
Internal Medicine, Dow Medical College, Dow University of Health Sciences (duhs), Karachi, PAK.
Cureus. 2018 May 5;10(5):e2582. doi: 10.7759/cureus.2582.
Vitamin B12 is essential for the development of healthy nerves and red blood cells. Vitamin B12 deficiency is becoming widespread and most commonly affects elderly, pregnant women, vegetarians, and patients with renal or intestinal diseases. Either parenteral vitamin B12 treatment or high-dose oral vitamin B12 treatment is an effective therapy regardless of etiology. Parenteral therapy using the intramuscular route is considered the most familiar treatment for vitamin B12 deficiency. Anaphylactic reaction after intramuscular injection is an uncommon and potentially serious side effect. In this study, we are documenting a case of anaphylactic reaction in a 55-year-old woman after her second dose of intramuscular injection of cyanocobalamin. The purpose of this case report is to highlight the need to understand the rare life-threatening side effect of intramuscular cyanocobalamin. Health care providers should be vigilant while administering the intramuscular injection of cyanocobalamin to vitamin B12 deficient patients.
维生素B12对健康神经和红细胞的发育至关重要。维生素B12缺乏症正变得普遍，最常影响老年人、孕妇、素食者以及患有肾脏或肠道疾病的患者。无论病因如何，肠外维生素B12治疗或高剂量口服维生素B12治疗都是有效的疗法。使用肌肉注射途径的肠外疗法被认为是治疗维生素B12缺乏症最常见的方法。肌肉注射后的过敏反应是一种罕见但可能严重的副作用。在本研究中，我们记录了一名55岁女性在第二次肌肉注射氰钴胺后发生过敏反应的病例。本病例报告的目的是强调了解肌肉注射氰钴胺这种罕见的危及生命副作用的必要性。医疗保健人员在给维生素B12缺乏的患者进行肌肉注射氰钴胺时应保持警惕。
