Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering of, Ministry of Education, College of Chemistry, Peking University, Beijing, 100871, P. R. China.
College of Chemistry and Materials Science, Hebei Normal University, Shijiazhuang, 050024, P. R. China.
Chemistry. 2018 Dec 20;24(72):19122-19135. doi: 10.1002/chem.201802536. Epub 2018 Oct 30.
Alkenyl magnesium compounds have received much attention in synthetic organic chemistry because of their high reactivity. This review summarizes three types of alkenyl magnesium compounds which contain at least one [Mg-C=C] fragment, for example, (1) alkenyl Grignard reagents prepared by halogen-magnesium exchange reaction; (2) alkenyl magnesium carbenoids prepared by halogen-magnesium exchange reaction or sulfoxide-magnesium exchange reaction; (3) magnesacarbocycles containing at least one alkenyl magnesium bond prepared from Zr- or Ti-catalyzed cyclomagnesation or transmetalation, as well as their further reactions and applications.
烯基镁化合物因其高反应性而在合成有机化学中受到广泛关注。本综述总结了三种类型的烯基镁化合物，它们都至少含有一个[Mg-C=C]片段，例如：（1）通过卤代镁交换反应制备的烯基格氏试剂；（2）通过卤代镁交换反应或亚砜镁交换反应制备的烯基镁卡宾；（3）通过锆或钛催化的环镁化或转金属化反应制备的至少含有一个烯基镁键的镁杂环化合物，以及它们的进一步反应和应用。
