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光子放疗中3D打印患者支撑或固定装置的临床委托框架。

A framework for clinical commissioning of 3D-printed patient support or immobilization devices in photon radiotherapy.

作者信息

Meyer Tyler, Quirk Sarah, D'Souza Malgorzata, Spencer David, Roumeliotis Michael

机构信息

Department of Oncology, University of Calgary, Calgary, AB, Canada.

Department of Physics and Astronomy, University of Calgary, Calgary, AB, Canada.

出版信息

J Appl Clin Med Phys. 2018 Sep;19(5):499-505. doi: 10.1002/acm2.12408. Epub 2018 Jul 8.

Abstract

PURPOSE

The objective of this work is to outline a framework for dosimetric characterization that will comprehensively detail the clinical commissioning steps for 3D-printed materials applied as patient support or immobilization devices in photon radiotherapy. The complex nature of 3D-printed materials with application to patient-specific configurations requires careful consideration. The framework presented is generalizable to any 3D-printed object where the infill and shell combinations are unknown.

METHODS

A representative cylinder and wedge were used as test objects to characterize devices that may be printed of unknown, patient-specific dimensions. A case study of a 3D-printed CSI immobilization board was presented as an example of an object of known, but adaptable dimensions and proprietary material composition. A series of measurements were performed to characterize the material's kV radiologic properties, MV attenuation measurements and calculations, energy spectrum water equivalency, and surface dose measurements. These measurements complement the recommendations of the AAPM's TG176 to characterize the additional complexity of 3D-printed materials for use in a clinical radiotherapy environment.

RESULTS

The dosimetric characterization of 3D-printed test objects and a case study device informed the development of a step-by-step template that can easily be followed by clinicians to accurately and safely utilize 3D-printed materials as patient-specific support or immobilization devices.

CONCLUSIONS

A series of steps is outlined to provide a formulaic approach to clinically commission 3D-printed materials that may possess varying material composition, infill patterns, and patient-specific dimensions.

摘要

目的

本研究的目的是概述一个剂量学表征框架,该框架将全面详细地阐述在光子放射治疗中用作患者支撑或固定装置的3D打印材料的临床调试步骤。3D打印材料应用于患者特定配置的复杂性质需要仔细考虑。所提出的框架可推广到任何填充和外壳组合未知的3D打印物体。

方法

使用代表性的圆柱体和楔形物作为测试对象,以表征可能打印出的尺寸未知的患者特定装置。以3D打印的CSI固定板的案例研究为例,说明一个尺寸已知但可调整且材料成分专有的物体。进行了一系列测量,以表征材料的千伏放射学特性、兆伏衰减测量和计算、能谱水等效性以及表面剂量测量。这些测量补充了美国医学物理学家协会(AAPM)TG176的建议,以表征用于临床放射治疗环境的3D打印材料的额外复杂性。

结果

3D打印测试对象和一个案例研究装置的剂量学表征为临床医生开发了一个逐步模板,临床医生可以轻松遵循该模板,以准确、安全地将3D打印材料用作患者特定的支撑或固定装置。

结论

概述了一系列步骤,以提供一种公式化方法,用于临床调试可能具有不同材料成分、填充模式和患者特定尺寸的3D打印材料。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9050/6123103/ab94ad4a46c5/ACM2-19-499-g001.jpg

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