Associate Professor, Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX.
Professor, Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX.
CA Cancer J Clin. 2018 Sep;68(5):340-355. doi: 10.3322/caac.21462. Epub 2018 Jul 9.
Therapies in oncology have evolved rapidly over the last years. At the same pace, supportive care for patients receiving cancer therapy has also evolved, allowing patients to safely receive the newest advances in treatment in both an inpatient and outpatient basis. The recognition of the role of infection control and prevention (ICP) in the outcomes of patients living with cancer has been such that it is now a requirement for hospitals and involves multidisciplinary groups. Some unique aspects of ICP for patients with cancer that have gained momentum over the past few decades include catheter-related infections, multidrug-resistant organisms, community-acquired viral infections, and the impact of the health care environment on the horizontal transmission of organisms. Furthermore, as the potential for infections to cross international borders has increased, alertness for outbreaks or new infections that occur outside the area have become constant. As the future approaches, ICP in immunocompromised hosts will continue to integrate emerging disciplines, such as antibiotic stewardship and the microbiome, and new techniques for environmental cleaning and for controlling the spread of infections, such as whole-genome sequencing. CA Cancer J Clin 2018;000:000-000. © 2018 American Cancer Society.
近年来,肿瘤学领域的治疗方法发展迅速。与此同时,癌症治疗患者的支持性护理也在不断发展,使患者能够安全地在住院和门诊基础上接受最新的治疗进展。人们已经认识到感染控制和预防(ICP)在癌症患者预后中的作用,因此它现在是医院的一项要求,并涉及多学科小组。过去几十年中,癌症患者 ICP 方面的一些独特方面得到了发展,包括导管相关感染、多药耐药菌、社区获得性病毒感染,以及医疗环境对病原体水平传播的影响。此外,随着感染跨越国际边界的可能性增加,对该地区以外发生的疫情或新感染的警惕性也在不断提高。随着未来的到来,免疫功能低下宿主的 ICP 将继续整合新兴学科,如抗生素管理和微生物组,以及用于环境清洁和控制感染传播的新技术,如全基因组测序。CA Cancer J Clin 2018;000:000-000。©2018 美国癌症协会。