Matsumoto A, Murakami S, Arai Y, Osanai M
Brain Res. 1985 Nov 18;347(2):363-7. doi: 10.1016/0006-8993(85)90200-8.
The medial preoptic area (POA) of newborn female rats was transplanted into the third ventricle of young adult (2 months of age) and aged (27 months of age) female rats. The grafted POA tissues were examined ultrastructurally 2 months after transplantation. The mean numbers of axodendritic shaft and spine synapses in the POA transplants in both young adult and aged female rats were much greater than those in the medial POA of newborn female rats. These results suggest that the neuronal substrates in the medial POA grafts develop well in the brain of the aged female rats.
将新生雌性大鼠的内侧视前区（POA）移植到成年雌性大鼠（2月龄）和老年雌性大鼠（27月龄）的第三脑室内。移植后2个月对移植的POA组织进行超微结构检查。成年雌性大鼠和老年雌性大鼠POA移植物中轴突树突干突触和棘突触的平均数量均远多于新生雌性大鼠内侧POA中的数量。这些结果表明，内侧POA移植物中的神经元基质在老年雌性大鼠脑内发育良好。
