Glycomimetics: Design, Synthesis, and Therapeutic Applications.
作者信息
Compain Philippe
机构信息
Laboratoire d'Innovation Moléculaire et Application (LIMA), Université de Strasbourg, Université de Haute-Alsace, CNRS (UMR 7042), Equipe Synthèse Organique et Molécules Bioactives (SYBIO), Ecole Européenne de Chimie, Polymères et Matériaux, 25 rue Becquerel, 67000 Strasbourg, France.
出版信息
Molecules. 2018 Jul 7;23(7):1658. doi: 10.3390/molecules23071658.
Abstract
摘要
相似文献
1
Glycomimetics: Design, Synthesis, and Therapeutic Applications.糖模拟物：设计、合成及治疗应用
Molecules. 2018 Jul 7;23(7):1658. doi: 10.3390/molecules23071658.
2
Synthesis of sulfonamide-bridged glycomimetics.糖基模拟物的磺酰胺桥联合成。
J Org Chem. 2011 May 6;76(9):2965-75. doi: 10.1021/jo2001269. Epub 2011 Mar 29.
3
From carbohydrate leads to glycomimetic drugs.从碳水化合物衍生出拟糖药物。
Nat Rev Drug Discov. 2009 Aug;8(8):661-77. doi: 10.1038/nrd2852. Epub 2009 Jul 24.
4
Synthesis of thiohydantoin-castanospermine glycomimetics as glycosidase inhibitors.硫代乙内酰脲-栗精胺糖模拟物作为糖苷酶抑制剂的合成。
J Org Chem. 2009 May 1;74(9):3595-8. doi: 10.1021/jo900231b.
5
Carbohydrate-based bioactive compounds for medicinal chemistry applications.用于药物化学应用的基于碳水化合物的生物活性化合物。
Mini Rev Med Chem. 2011 Jan;11(1):39-54. doi: 10.2174/138955711793564060.
6
Solid phase synthesis of a prototype of a new class of biomimetic receptors for anionic carbohydrates.新型阴离子碳水化合物仿生受体原型的固相合成
Org Biomol Chem. 2007 Mar 7;5(5):787-91. doi: 10.1039/b613660e. Epub 2007 Jan 26.
7
Carbohydrate mimetics as potential drug candidates.作为潜在药物候选物的碳水化合物模拟物。
Mini Rev Med Chem. 2012 Dec;12(14):1433. doi: 10.2174/138955712803832717.
8
Biomimetic carbohydrate recognition.仿生糖识别。
Chem Soc Rev. 2020 May 7;49(9):2531-2545. doi: 10.1039/c9cs00391f. Epub 2020 Mar 19.
9
Synthesis of glycopolymers by controlled radical polymerization techniques and their applications.通过控制自由基聚合技术合成糖聚合物及其应用。
Chembiochem. 2012 Nov 26;13(17):2478-87. doi: 10.1002/cbic.201200480. Epub 2012 Nov 6.
10
Synthesis and conformational and biological aspects of carbasugars.碳环糖的合成、构象及生物学特性
Chem Rev. 2007 May;107(5):1919-2036. doi: 10.1021/cr0203701.
引用本文的文献
1
Controlling Glycan Folding with Ionic Functional Groups.利用离子官能团控制聚糖折叠
J Am Chem Soc. 2025 May 7;147(18):15126-15135. doi: 10.1021/jacs.4c17992. Epub 2025 Apr 24.
2
Synthesis of -glycosyl amides: conformational analysis and evaluation as inhibitors of β-galactosidase from .-糖基酰胺的合成：构象分析及其作为来自……的β-半乳糖苷酶抑制剂的评价
RSC Adv. 2024 Jan 16;14(4):2659-2672. doi: 10.1039/d3ra07763b. eCollection 2024 Jan 10.
3
On-water synthesis of glycosyl selenocyanate derivatives and their application in the metal free organocatalytic preparation of nonglycosidic selenium linked pseudodisaccharide derivatives.糖基硒氰酸酯衍生物的水相合成及其在无金属有机催化制备非糖苷硒连接假二糖衍生物中的应用
RSC Adv. 2021 Mar 15;11(18):10902-10911. doi: 10.1039/d1ra00711d. eCollection 2021 Mar 10.
4
Synthesis of novel seven-membered carbasugars and evaluation of their glycosidase inhibition potentials.新型七元碳环糖的合成及其糖苷酶抑制潜力评估。
RSC Adv. 2021 Mar 2;11(16):9410-9420. doi: 10.1039/d1ra00804h. eCollection 2021 Mar 1.
5
A benzoxazole derivative as an inhibitor of anaerobic choline metabolism by human gut microbiota.一种作为人肠道微生物群厌氧胆碱代谢抑制剂的苯并恶唑衍生物。
RSC Med Chem. 2020 Aug 28;11(12):1402-1412. doi: 10.1039/d0md00218f. eCollection 2020 Dec 17.
6
Synthesis and Evaluation of Novel Iminosugars Prepared from Natural Amino Acids.从天然氨基酸制备新型亚氨基糖的合成与评价。
Molecules. 2021 Jan 13;26(2):394. doi: 10.3390/molecules26020394.
7
Amino Acid-Based Synthesis and Glycosidase Inhibition of Cyclopropane-Containing Iminosugars.基于氨基酸的含环丙烷亚氨基糖的合成及糖苷酶抑制作用
ACS Omega. 2020 Dec 2;5(49):31821-31830. doi: 10.1021/acsomega.0c04589. eCollection 2020 Dec 15.
8
An overview of carbohydrate-based carbonic anhydrase inhibitors.碳水化合物衍生碳酸酐酶抑制剂概述。
J Enzyme Inhib Med Chem. 2020 Dec;35(1):1906-1922. doi: 10.1080/14756366.2020.1825409. Epub 2020 Oct 20.
9
Targeting Galectins With Glycomimetics.用糖模拟物靶向半乳糖凝集素
Front Chem. 2020 Aug 7;8:593. doi: 10.3389/fchem.2020.00593. eCollection 2020.
10
Synthesis and Therapeutic Applications of Iminosugars in Cystic Fibrosis.合成与应用在囊性纤维化治疗中的亚氨基糖
Int J Mol Sci. 2020 May 9;21(9):3353. doi: 10.3390/ijms21093353.
本文引用的文献
1
Glycoside Mimics from Glycosylamines: Recent Progress.糖基胺的糖苷类似物：最新进展。
Molecules. 2018 Jul 2;23(7):1612. doi: 10.3390/molecules23071612.
2
Probing the Inhibitor versus Chaperone Properties of sp²-Iminosugars towards Human β-Glucocerebrosidase: A Picomolar Chaperone for Gaucher Disease.探究 sp²-亚氨基糖对人β-葡糖苷脑苷脂酶的抑制剂与伴侣蛋白性质：戈谢病的皮摩尔级伴侣蛋白。
Molecules. 2018 Apr 17;23(4):927. doi: 10.3390/molecules23040927.
3
One-Pot, Highly Stereoselective Synthesis of Dithioacetal-α,α-Diglycosides.一锅法、高立体选择性合成二硫缩醛-α,α-二糖苷。
Molecules. 2018 Apr 15;23(4):914. doi: 10.3390/molecules23040914.
4
Potent GH20 N-Acetyl-β-d-hexosaminidase Inhibitors: N-Substituted 3-acetamido-4-amino-5-hydroxymethyl-cyclopentanediols.强效 GH20 N-乙酰-β-d-己糖苷酶抑制剂：N-取代的 3-乙酰氨基-4-氨基-5-羟甲基环己烷二醇。
Molecules. 2018 Mar 20;23(3):708. doi: 10.3390/molecules23030708.
5
Synthesis of New C- and N-β-d-Glucopyranosyl Derivatives of Imidazole, 1,2,3-Triazole and Tetrazole, and Their Evaluation as Inhibitors of Glycogen Phosphorylase.新型咪唑、1,2,3-三唑和四唑的 C-和 N-β-d-葡萄糖苷衍生物的合成及其作为糖原磷酸化酶抑制剂的评价。
Molecules. 2018 Mar 15;23(3):666. doi: 10.3390/molecules23030666.
6
Synthesis of O-Amino Sugars and Nucleosides.O-氨基糖和核苷的合成。
Molecules. 2018 Mar 12;23(3):641. doi: 10.3390/molecules23030641.
7
Convergent Synthesis of N,S-bis Glycosylquinolin-2-ones via a Pd-G3-XantPhos Precatalyst Catalysis.通过 Pd-G3-XantPhos 预催化剂催化的 N,S-双糖苷喹啉-2-酮的汇聚合成。
Molecules. 2018 Feb 26;23(3):519. doi: 10.3390/molecules23030519.
8
Probing the Influence of Linker Length and Flexibility in the Design and Synthesis of New Trehalase Inhibitors.探究连接基团长度和柔性对新型海藻糖酶抑制剂设计和合成的影响。
Molecules. 2018 Feb 16;23(2):436. doi: 10.3390/molecules23020436.
9
Toward a Molecular Lego Approach for the Diversity-Oriented Synthesis of Cyclodextrin Analogues Designed as Scaffolds for Multivalent Systems.迈向一种分子乐高方法，用于以多样性为导向合成环糊精类似物，设计为多价体系的支架。
J Org Chem. 2015 Nov 6;80(21):10719-33. doi: 10.1021/acs.joc.5b01938. Epub 2015 Oct 26.
10
Synthesis of α-glycosyl thiols by stereospecific ring-opening of 1,6-anhydrosugars.通过 1,6-脱水糖的立体特异性开环合成 α-糖基硫醇。
J Org Chem. 2011 Dec 16;76(24):10187-97. doi: 10.1021/jo202069y. Epub 2011 Nov 16.
Zotero 插件