Campbell Amber R, Kinvig Karen, Côté Hélène Cf, Lester Richard T, Qiu Annie Q, Maan Evelyn J, Alimenti Ariane, Pick Neora, Murray Melanie Cm
Division of Experimental Medicine, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Oak Tree Clinic, British Columbia Women's Hospital, Vancouver, BC, Canada.
JMIR Mhealth Uhealth. 2018 Jul 9;6(7):e152. doi: 10.2196/mhealth.9493.
Improving adherence to combined antiretroviral therapy (cART) can be challenging, especially among vulnerable populations living with HIV. Even where cART is available free of charge, social determinants of health act as barriers to optimal adherence rates. Patient-centered approaches exploiting mobile phone communications (mHealth) have been shown to improve adherence to cART and promote achievement of suppressed HIV plasma viral loads. However, data are scarce on the health care provider (HCP) time commitments and health care costs associated with such interventions. This knowledge is needed to inform policy and programmatic implementation.
The purpose of this study was to approximate the resources required and to provide an estimate of the costs associated with running an mHealth intervention program to improve medication adherence in people living with HIV (PLWH).
This prospective study of HCP utilization and costs was embedded within a repeated measures effectiveness study of the WelTel short-message service (SMS) mHealth program. The study included 85 vulnerable, nonadherent PLWH in Vancouver, Canada, and resulted in improved medication adherence and HIV plasma viral load among participants. Study participants were provided mobile phones with unlimited texting (where required) and received weekly bidirectional text messages to inquire on their status for one year. A clinic nurse triaged and managed participants' responses, immediately logging all patient interactions by topic, HCP involvement, and time dedicated to addressing issues raised by participants. Interaction costs were determined in Canadian dollars based on HCP type, median salary within our health authority, and their time utilized as part of the intervention.
Participant-identified problems within text responses included health-related, social, and logistical issues. Taken together, management of problems required a median of 43 minutes (interquartile range, IQR 17-99) of HCP time per participant per year, for a median yearly cost of Can $36.72 (IQR 15.50-81.60) per participant who responded with at least one problem. The clinic nurse who monitored the texts solved or managed 65% of these issues, and the remaining were referred to a variety of other HCPs. The total intervention costs, including mobile phones, plans, and staffing were a median Can $347.74/highly vulnerable participant per year for all participants or Can $383.18/highly vulnerable participant per year for those who responded with at least one problem.
Bidirectional mHealth programs improve HIV care and treatment outcomes for PLWH. Knowledge about the HCP cost associated, here less than Can $50/year, provides stakeholders and decision makers with information relevant to determining the feasibility and sustainability of mHealth programs in a real-world setting.
ClinicalTrials.gov NCT02603536; https://clinicaltrials.gov/ct2/show/NCT02603536 (Archived by WebCite at http://www.webcitation.org/70IYqKUjV).
提高对抗逆转录病毒联合疗法(cART)的依从性可能具有挑战性,尤其是在感染艾滋病毒的弱势群体中。即使在免费提供cART的地方,健康的社会决定因素也成为实现最佳依从率的障碍。已证明,利用移动电话通信(移动健康)的以患者为中心的方法可提高对cART的依从性,并促进实现艾滋病毒血浆病毒载量的抑制。然而,关于医疗服务提供者(HCP)的时间投入以及与此类干预措施相关的医疗保健成本的数据却很少。需要这些信息来为政策和项目实施提供依据。
本研究的目的是估算所需资源,并估计开展一项移动健康干预项目以提高艾滋病毒感染者(PLWH)药物依从性的相关成本。
这项关于HCP利用情况和成本的前瞻性研究纳入了一项关于WelTel短信移动健康项目的重复测量有效性研究。该研究纳入了加拿大温哥华85名易受影响、不依从治疗的PLWH,结果参与者的药物依从性和艾滋病毒血浆病毒载量得到了改善。为研究参与者提供了不限短信数量的手机(如有需要),并在一年内每周发送双向短信询问他们的状况。一名诊所护士对参与者的回复进行分类和管理,立即按主题、HCP参与情况以及处理参与者提出问题所花费的时间记录所有患者互动。根据HCP类型、我们卫生机构内的中位数工资以及他们作为干预一部分所使用的时间,以加元确定互动成本。
参与者在短信回复中提出的问题包括与健康、社会和后勤相关的问题。总体而言,问题管理每位参与者每年需要HCP中位数43分钟(四分位间距,IQR 17 - 99)的时间,对于至少提出一个问题的参与者,每年中位数成本为36.72加元(IQR 15.50 - 81.60)。监测短信的诊所护士解决或管理了65%的这些问题,其余问题则转介给了各种其他HCP。包括手机、套餐和人员配备在内的总干预成本,所有参与者每年每位高度易受影响参与者中位数为347.74加元,对于至少提出一个问题的参与者,每年每位高度易受影响参与者中位数为383.18加元。
双向移动健康项目改善了PLWH的艾滋病毒护理和治疗结果。此处所了解的与HCP相关的成本每年不到50加元,为利益相关者和决策者提供了与确定移动健康项目在现实环境中的可行性和可持续性相关的信息。
ClinicalTrials.gov NCT02603536;https://clinicaltrials.gov/ct2/show/NCT02603536(由WebCite存档于http://www.webcitation.org/70IYqKUjV)