Rollins School of Public Health, Emory University, Atlanta, Georgia.
Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia.
Am J Trop Med Hyg. 2018 Sep;99(3):713-715. doi: 10.4269/ajtmh.18-0069. Epub 2018 Jul 5.
Because anemia is one of the markers of morbidity associated with schistosomiasis, it has been proposed as a potential measure to evaluate the impact of control programs. However, anemia is also a common consequence of malaria, and schistosomiasis and malaria are often co-endemic. To estimate the attributable fraction of anemia due to and infections, we applied a log-binomial model to four studies measuring these parameters of a combined 5,849 children in western Kenya. In our studies, malaria contributed 23.3%, schistosomiasis contributed 6.6%, and co-infection contributed 27.6% of the anemia. We conclude that in areas where and are co-endemic, the contribution of schistosomiasis to anemia is masked by anemia resulting from malaria, thus limiting anemia as a useful measure for schistosomiasis control programs in these settings.
由于贫血是与血吸虫病相关的发病率的标志之一，因此它被提议作为评估控制规划影响的潜在措施。然而，贫血也是疟疾的常见后果，并且血吸虫病和疟疾通常是共流行的。为了估计因 和 感染导致的贫血的归因分数，我们应用对数二项式模型对四项研究进行了分析，这些研究测量了来自肯尼亚西部的 5849 名儿童的这些参数。在我们的研究中，疟疾导致的贫血占 23.3%，血吸虫病导致的贫血占 6.6%，混合感染导致的贫血占 27.6%。我们的结论是，在 和 共流行的地区，疟疾导致的贫血掩盖了血吸虫病导致的贫血，从而限制了贫血作为这些地区血吸虫病控制规划的有用措施。
