Eboni Audred Cristina Biondo, Cardoso Mariana, Dias Felipe Moreira, da Gama Paulo Diniz, Gomes Sidney, Goncalves Marcus Vinicius Magno, Machado Suzana Costa Nunes, da Nobrega Adaucto Wanderley, Parolin Monica Fiuza Konke, Paz Sonia Castedo, Ruocco Heloisa Helena, Scorcine Claudio, Siquineli Fabio, Spessotto Caroline Vieira, Tauil Carlos Bernardo, Fragoso Yara Dadalti
Department of Neurology, Universidade da Regiao de Joinville, Joinville, SC, Brazil.
Department of Neurology, Universidade Metropolitana de Santos, Santos, SP, Brazil.
Dement Neuropsychol. 2018 Apr-Jun;12(2):212-215. doi: 10.1590/1980-57642018dn12-020015.
Alexithymia is a personality trait characterized by difficulties identifying and describing feelings. Some researchers describe high levels of alexithymia among patients with multiple sclerosis (MS) but literature data on this subject are scarce.
The objective of the present study was to characterize findings of alexithymia in patients with MS.
This cross-sectional case-control study included 180 patients with MS and a matched control group. Data for patients with MS included disease duration, number of demyelinating relapses and degree of neurological disability, as assessed by the Expanded Disability Scale Score (EDSS). In addition, the Hospital Anxiety and Depression (HAD) scale and the Toronto Alexithymia Scale (TAS) were used.
There were 126 women and 54 men in each group, with median age of 37 years and median education of 16 years. Patients with MS had higher degrees of depression (p<0.01), anxiety (p=0.01) and alexithymia (p<0.01) than did control subjects. For individuals with MS, depressive traits (p<0.01), anxious traits (p=0.03), higher age (p=0.02), lower education level (p=0.02), higher degree of disability (p<0.01) and not being actively employed (p=0.03) were associated with higher rates of alexithymia.
Alexithymia was a relevant finding in patients with MS.
述情障碍是一种人格特质，其特征是难以识别和描述情感。一些研究人员描述了多发性硬化症（MS）患者中述情障碍水平较高，但关于这一主题的文献数据很少。
本研究的目的是描述MS患者述情障碍的表现。
这项横断面病例对照研究纳入了180例MS患者和一个匹配的对照组。MS患者的数据包括疾病持续时间、脱髓鞘复发次数和神经功能残疾程度，通过扩展残疾量表评分（EDSS）进行评估。此外，还使用了医院焦虑和抑郁量表（HAD）和多伦多述情障碍量表（TAS）。
每组中有126名女性和54名男性，中位年龄为37岁，中位受教育年限为16年。MS患者的抑郁程度（p<0.01）、焦虑程度（p=0.01）和述情障碍程度（p<0.01）均高于对照组。对于MS患者，抑郁特质（p<0.01）、焦虑特质（p=0.03）、年龄较大（p=0.02）、教育水平较低（p=0.02）、残疾程度较高（p<0.01）以及未积极就业（p=0.03）与述情障碍发生率较高相关。
述情障碍是MS患者的一个相关表现。
