Mendelsohn Abie H, Remacle Marc Joseph
Department of Head and Neck Surgery, UCLA David Geffen School of Medicine, Los Angeles, CA, United States.
Department of Otorhinolaryngology Head and Neck Surgery, Centre Hospitalier de Luxembourg - Clinique d'Eich, Luxembourg, Luxembourg.
Front Oncol. 2018 Jun 22;8:231. doi: 10.3389/fonc.2018.00231. eCollection 2018.
The surgical treatment of glottic, or vocal cord, cancer has seen considerable progression over the past several decades. Specifically, there has been a stark transition from open partial laryngectomy surgery to endoscopic laser microsurgical techniques which have been inspired in large part by two landmark studies: Professor Wolfgang Steiner's original case series describing transoral laser microsurgery for glottic cancer (1993) and the European Laryngological Society's (ELS) classification scheme (2000). We performed a comprehensive review of published literature to characterize the pattern of this novel modality as compared with two landmark studies over the past four decades.
An English literature search was conducted on PubMed for available original investigations on surgical treatment of glottic laryngeal cancer published over the past 40 years. Our Boolean criteria included the following terms: cancer, glottic, laryngeal, surgery, endoscopic, and laser. The publication rates were calculated as annual compound growth as well as corrected growth rates as defined by the Fisher equation for inflation effects.
Our review identified 13,372 studies covering larynx cancer and 3,557 studies covering glottic cancer original studies. Among these, we analyzed the compound annual growth rates and correct growth rates for three distinct publication periods or epochs, prior to 1993, 1993-1999, and 2000-2017. For all but two of the search term groups covering both glottic cancer as well as larynx cancer, there was a substantial growth improvement in the time period following the ELS classification scheme as compared with the growth rate of the time period following Steiner's case series.
The progress toward minimally invasive treatment of glottic cancer has progressed steadily over the past several decades. Analysis of publication show increased growth during the time period following the ELS classification scheme over the time period following Steiner's landmark study. A mistake would be concluding any diminished importance of Professor Steiner's work, instead, our analysis demonstrates the wide-spread adoption of the endoscopic laser cordectomy procedure following the ELS classification system. Complex surgical techniques such as transoral laser microsurgery are optimally disseminated within well-defined classification schemes, though further validation is warranted.
在过去几十年中，声门癌或声带癌的外科治疗取得了显著进展。具体而言，从开放性部分喉切除术到内镜激光显微外科技术发生了明显转变，这在很大程度上受到两项具有里程碑意义的研究的启发：沃尔夫冈·施泰纳教授最初描述声门癌经口激光显微手术的病例系列（1993年）以及欧洲喉科学会（ELS）的分类方案（2000年）。我们对已发表的文献进行了全面回顾，以描述这种新方法与过去四十年来的两项具有里程碑意义的研究相比的模式。
在PubMed上进行英文文献检索，以查找过去40年中发表的关于声门喉癌外科治疗的现有原始研究。我们的布尔检索标准包括以下术语：癌症、声门、喉、手术、内镜和激光。出版率计算为年度复合增长率以及由费雪方程定义的考虑通货膨胀影响的校正增长率。
我们的综述确定了13372项涵盖喉癌的研究和3557项涵盖声门癌的原始研究。其中，我们分析了三个不同出版时期或阶段（1993年之前、1993 - 1999年以及2000 - 2017年）的复合年增长率和校正增长率。对于除两个同时涵盖声门癌和喉癌的检索词组之外的所有检索词组，与施泰纳病例系列之后时期的增长率相比，ELS分类方案之后时期的增长有显著改善。
在过去几十年中，声门癌微创治疗的进展稳步推进。对出版物的分析表明，ELS分类方案之后时期的增长高于施泰纳具有里程碑意义的研究之后时期。得出施泰纳教授工作重要性降低的结论将是错误的，相反，我们的分析表明在ELS分类系统之后内镜激光声带切除术得到了广泛采用。经口激光显微手术等复杂手术技术在明确的分类方案内得到了最佳传播，不过仍需进一步验证。
