Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, Dalhousie University, 3rd Floor Dickson Building, 5820 University Avenue, Halifax, NS B3H 1V7.
J Otolaryngol Head Neck Surg. 2011 Jun;40(3):205-10.
In this study, we sought to determine current trends in the management of glottic cancer in Canada. We further sought to determine the approach to margin status following treatment of glottic cancer.
An online survey was distributed to all head and neck (H&N) surgeons and all radiation oncologists (ROs) in Canada. Respondents were asked to choose management recommendations for a series of tumour descriptions and to offer their opinion of margin evaluation. The results were compiled and analyzed using descriptive statistics for frequencies and chi-square analysis for comparison between H&N surgeons and ROs.
The survey attained a response rate of 60% among H&N surgeons and 20% among ROs. There was a significant difference in choice of management for T1a, T1b, T2a, and T2b tumours, with ROs heavily favouring radiation therapy and H&N surgeons' opinions divided between radiation therapy and transoral laser microsurgery (TLM). There was no significant difference of opinion in the treatment of T3 and T4a tumours. The size of an adequate margin was significantly different between ROs and H&N surgeons, as was the management of a positive margin.
Compared to previous surveys, this study reflects a move toward TLM as the preferred treatment for T1a glottic cancer among H&N surgeons, whereas ROs continue to favour radiation therapy. The results also show a split in opinions among H&N surgeons with respect to TLM versus radiation therapy for early-stage glottic tumours. The study underscores a difference of opinion between specialties regarding the management of glottic cancer and the need for a definitive comparison study to guide recommendations.
本研究旨在确定加拿大喉癌治疗的现状,并进一步确定喉癌治疗后切缘状态的处理方法。
我们向加拿大所有头颈(H&N)外科医生和所有放射肿瘤学家(ROs)发放了在线调查。要求受访者为一系列肿瘤描述选择管理建议,并对切缘评估提出意见。使用频率描述性统计和 H&N 外科医生与 ROs 之间的卡方分析对结果进行编译和分析。
H&N 外科医生的调查回复率为 60%,ROs 的回复率为 20%。T1a、T1b、T2a 和 T2b 肿瘤的管理选择存在显著差异,ROs 强烈倾向于放射治疗,而 H&N 外科医生的意见则在放射治疗和经口激光微创手术(TLM)之间存在分歧。T3 和 T4a 肿瘤的治疗意见无显著差异。ROs 和 H&N 外科医生之间的合适切缘大小存在显著差异,阳性切缘的处理也是如此。
与之前的调查相比,本研究反映了 H&N 外科医生将 TLM 作为 T1a 声门癌首选治疗方法的趋势,而 ROs 继续倾向于放射治疗。研究结果还表明,H&N 外科医生在 TLM 与放射治疗早期声门肿瘤方面存在意见分歧。该研究强调了不同专业在喉癌管理方面存在意见分歧,需要进行确定性比较研究来指导建议。