导致新发1型糖尿病患者出现高甘油三酯血症的载脂蛋白E异构体。
ApoE isoform leading to hypertriglyceridemia in new onset type 1 diabetes.
作者信息
Keefe Christel, Lawson Sarah
机构信息
Cincinnati Children's Hospital Medical Center University of Cincinnati Cincinnati OH USA.
出版信息
Clin Case Rep. 2018 May 24;6(7):1287-1290. doi: 10.1002/ccr3.1584. eCollection 2018 Jul.
Abstract
We report a case of pediatric diabetic ketoacidosis (DKA) with significant hypertriglyceridemia. The patient was found to have the e3/ e4 isoform of ApoE, increasing risk of hypertriglyceridemia in DKA. We suggest further genetic investigation for patients presenting with severe hypertriglyceridemia and DKA.
摘要
我们报告了一例患有严重高甘油三酯血症的儿童糖尿病酮症酸中毒（DKA）病例。该患者被发现携带载脂蛋白E的e3/e4异构体，这增加了其在DKA中发生高甘油三酯血症的风险。我们建议对出现严重高甘油三酯血症和DKA的患者进行进一步的基因研究。
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