Tiperneni Raghu, Padappayil Rana P, Mohan Gaurav, Patton Chandler
Internal Medicine, Rutgers Health/Monmouth Medical Center, United States.
J Community Hosp Intern Med Perspect. 2022 Jul 4;12(4):85-88. doi: 10.55729/2000-9666.1074. eCollection 2022.
This case report describes the recurrence of diabetic ketoacidosis (DKA) leading to hypertriglyceridemia-induced pancreatitis. Hypertriglyceridemia is present in 2-5% of patients with diabetic ketoacidosis. Hypertriglyceridemiainduced pancreatitis occurs in up to 4% of patients with diabetic ketoacidosis and is a well-reported complication. This is the first case report to the author's knowledge, where the same patient had two separate episodes of acute pancreatitis that have been attributed to diabetic ketoacidosis and resultant severe hypertriglyceridemia, etiology determined to be medication non-compliance. DKA and acute pancreatitis can co-exist, and hypertriglyceridemia has been the predominant pathogenetic link between the two conditions. We also describe the pathophysiology and treatment of hyper-triglyceridemia-induced pancreatitis in diabetic ketoacidosis.
本病例报告描述了糖尿病酮症酸中毒（DKA）复发导致高甘油三酯血症性胰腺炎的情况。2%至5%的糖尿病酮症酸中毒患者存在高甘油三酯血症。高甘油三酯血症性胰腺炎在高达4%的糖尿病酮症酸中毒患者中发生，是一种报道充分的并发症。据作者所知，这是首例同一患者出现两次分别由糖尿病酮症酸中毒及由此导致的严重高甘油三酯血症引起的急性胰腺炎发作的病例报告，病因确定为药物治疗依从性差。DKA和急性胰腺炎可同时存在，高甘油三酯血症一直是这两种情况之间的主要发病机制联系。我们还描述了糖尿病酮症酸中毒中高甘油三酯血症性胰腺炎的病理生理学及治疗方法。
