State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, Department of Chemistry, Lanzhou University, Lanzhou, Gansu, China.
Org Biomol Chem. 2018 Jul 25;16(29):5232-5235. doi: 10.1039/c8ob01184b.
Al(NO3)3·9H2O as a nitro source for the synthesis of 3-nitrofurans from homopropargylic alcohols through Fe-catalyzed tandem cyclization is described. In this transformation, the substituted nitrofurans are obtained through nitration and cyclization. The substrate homopropargylic alcohols with different groups participate smoothly in this process and the desired substituted nitrofurans were obtained in moderate yields.
描述了以 Al(NO3)3·9H2O 为硝基源，通过 Fe 催化的串联环化反应，从偕丙醇类化合物合成 3-硝基呋喃的方法。在这个转化过程中，通过硝化和环化反应得到取代的硝基呋喃。不同取代基的偕丙醇类底物能顺利参与此过程，以中等收率得到目标取代的硝基呋喃。
