Do Jungmo, Lee Sin Woo, Jeh Seong Uk, Hwa Jeong Seok, Hyun Jae Seog, Choi See Min
Department of Urology, Gyeongsang National University Hospital, Jinju, Korea.
Can Urol Assoc J. 2018 Nov;12(11):E480-E483. doi: 10.5489/cuaj.5122. Epub 2018 Jun 8.
It has been reported that many methods prevent recurrence after transurethral resection of bladder tumour (TURBT) for non-muscle-invasive bladder cancer (NMIBC), but it has rarely been reported that overnight continuous saline irrigation is effective in preventing recurrence. The purpose of this study was to evaluate the efficacy of overnight continuous saline irrigation in preventing recurrence after TURBT.
We retrospectively studied patients with NMIBC who underwent TURBT from January 2010 to May 2015 at our institution. Patients who underwent cystoscopy every 12 weeks during the first year after surgery were included. Patients with cancer stage ≥pT2, lymph node metastasis, or distant metastasis were excluded. The overnight continuous saline irrigation (OCSI) group and the no irrigation group were compared and analyzed.
A total of 332 patients were included in the study. There were no differences in the basic characteristics of the patients between the two groups. In the OCSI group, the recurrence-free survival rate was higher than that in the no irrigation group, indicating that there was a significant difference between the two groups (p=0.032).
After TURBT surgery, OCSI may help prevent early recurrence of NMIBC.
据报道，有多种方法可预防非肌层浸润性膀胱癌（NMIBC）经尿道膀胱肿瘤切除术（TURBT）后的复发，但很少有报道称夜间持续膀胱冲洗在预防复发方面有效。本研究旨在评估夜间持续膀胱冲洗在预防TURBT术后复发中的疗效。
我们回顾性研究了2010年1月至2015年5月在我院接受TURBT的NMIBC患者。纳入术后第一年每12周接受一次膀胱镜检查的患者。排除癌症分期≥pT2、有淋巴结转移或远处转移的患者。对夜间持续膀胱冲洗（OCSI）组和未冲洗组进行比较分析。
本研究共纳入332例患者。两组患者的基本特征无差异。OCSI组的无复发生存率高于未冲洗组，表明两组之间存在显著差异（p = 0.032）。
TURBT术后，OCSI可能有助于预防NMIBC的早期复发。
