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对于低危非肌层浸润性膀胱癌经尿道切除术后无法进行膀胱内化疗单次灌注的情况,是否应推荐持续膀胱冲洗?

Should continuous bladder irrigation be recommended when single instillation of intravesical chemotherapy cannot be used after transurethral resection in low-risk non-muscle invasive bladder cancer?

作者信息

Chemi Joaquin, Villoldo Gustavo Martin

机构信息

Urology Department, Instituto Alexander Fleming, Cramer 1180, (1426) Ciudad Autónoma de Buenos Aires, Argentina.

出版信息

Bladder (San Franc). 2023 Mar 17;10:e21200002. doi: 10.14440/bladder.2023.848. eCollection 2023.

Abstract

Reducing the recurrence rate in patients with low-risk non-muscle invasive bladder cancer patients is a critical concern in the urologic community. The gold standard treatment is single instillation (SI) of intravesical chemotherapy after transurethral resection of bladder tumor (TURBT), but unfortunately, it is underused. Continuous bladder irrigation (CBI) after TURBT is an alternative strategy to SI for the prevention of bladder tumor implantation and recurrence. The aim of this review was to present the evidence that supports CBI after TURBT when SI is not possible.

摘要

降低低风险非肌层浸润性膀胱癌患者的复发率是泌尿外科领域的一个关键问题。金标准治疗方法是在经尿道膀胱肿瘤切除术(TURBT)后进行膀胱内化疗单剂量灌注(SI),但遗憾的是,这种方法未得到充分应用。TURBT术后持续膀胱冲洗(CBI)是一种替代SI的策略,用于预防膀胱肿瘤种植和复发。本综述的目的是阐述在无法进行SI时支持TURBT术后CBI的证据。

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本文引用的文献

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EAU Guidelines on Non-Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2016.
Eur Urol. 2017 Mar;71(3):447-461. doi: 10.1016/j.eururo.2016.05.041. Epub 2016 Jun 17.

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