Graduate Program in Social, Economic and Administrative Pharmacy, Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand, Viet Namese National Tuberculosis Program, Ha Noi.
Viet Namese National Tuberculosis Program, Ha Noi.
Int J Tuberc Lung Dis. 2018 Aug 1;22(8):912-917. doi: 10.5588/ijtld.18.0039.
Multidrug-resistant tuberculosis (MDR-TB) has become a major worldwide health problem. Various studies have been conducted on the cost of MDR-TB treatment; however, this has remained largely unexplored in Viet Nam.
To estimate the total cost of MDR-TB treatment at several health care facilities in Viet Nam.
A prospective, prevalence-based study was conducted at three selected centers from March to June 2016 in 204 patients, 102 of whom were treated for 9 months and 102 for 20 months. Direct medical costs were calculated using electronic hospital databases, while a questionnaire was used to interview participants for evaluating direct non-medical and indirect costs. Total costs were estimated from a societal perspective in 2017 USD.
Patients were mostly males aged 25-44 years. The average length of hospitalization in the 9-month treatment group was 168 ± 127 days; in the 20-month group, it was 671 ± 119 days. The average treatment cost for MDR-TB was respectively US$1480.34 ± 211.61 and US$2695.58 ± 294.98 for the 9- and 20-month treatment groups. Direct medical costs generally accounted for the highest proportion of the total costs, while the cost of pharmaceuticals and materials comprised the highest direct cost.
There was a significant difference in total costs among the three hospitals in the 9- and 20-month treatment groups.
耐多药结核病（MDR-TB）已成为全球主要的卫生问题。已经有许多关于 MDR-TB 治疗费用的研究，但在越南，这方面的研究还在很大程度上尚未得到探索。
评估越南几家医疗机构 MDR-TB 治疗的总费用。
前瞻性、基于患病率的研究于 2016 年 3 月至 6 月在三个选定的中心进行，共有 204 名患者参与，其中 102 名患者接受 9 个月的治疗，102 名患者接受 20 个月的治疗。直接医疗费用使用电子医院数据库计算，同时使用问卷访谈参与者评估直接非医疗和间接费用。2017 年美元的总费用从社会角度进行估算。
患者主要为 25-44 岁的男性。9 个月治疗组的平均住院时间为 168 ± 127 天；20 个月治疗组为 671 ± 119 天。MDR-TB 的平均治疗费用分别为 9 个月和 20 个月治疗组的 1480.34 ± 211.61 美元和 2695.58 ± 294.98 美元。直接医疗费用通常占总费用的最高比例，而药品和材料的成本占直接成本的最高比例。
在 9 个月和 20 个月治疗组中，三个医院的总费用存在显著差异。
