情绪失调作为慢性疼痛患者阿片类药物滥用和自杀倾向的一种跨诊断机制。
Emotion dysregulation as a transdiagnostic mechanism of opioid misuse and suicidality among chronic pain patients.
作者信息
Riquino Michael R, Priddy Sarah E, Howard Matthew O, Garland Eric L
机构信息
1University of Utah College of Social Work, 395 South 1500 East, Salt Lake City, UT 84112 USA.
Center on Mindfulness and Integrative Health Intervention Development, 395 South 1500 East, Salt Lake City, UT 84112 USA.
出版信息
Borderline Personal Disord Emot Dysregul. 2018 Jun 6;5:11. doi: 10.1186/s40479-018-0088-6. eCollection 2018.
BACKGROUND
Chronic pain is a prevalent condition that causes functional impairment and emotional suffering. To allay pain-induced suffering, opioids are often prescribed for chronic pain management. Yet, chronic pain patients on opioid therapy are at heightened risk for opioid misuse-behaviors that can lead to addiction and overdose. Relatedly, chronic pain patients are at elevated risk for suicidal ideation and suicidal behaviors.
MAIN BODY
Opioid misuse and suicidality are maladaptive processes aimed at alleviating the negative emotional hyperreactivity, hedonic hyporeactivity, and emotion dysregulation experienced by chronic pain patients on opioid therapy. In this review, we explore the role of emotion dysregulation in chronic pain. We then describe why emotionally dysregulated chronic pain patients are vulnerable to opioid misuse and suicidality in response to these negative affective states.
CONCLUSION
Emotion dysregulation is an important and malleable treatment target with the potential to reduce or prevent opioid misuse and suicidality among opioid-treated chronic pain patients.
背景
慢性疼痛是一种普遍存在的病症，会导致功能障碍和情绪痛苦。为减轻疼痛引起的痛苦，阿片类药物常被用于慢性疼痛管理。然而，接受阿片类药物治疗的慢性疼痛患者滥用阿片类药物的风险增加，这种行为可能导致成瘾和过量用药。相关地，慢性疼痛患者出现自杀意念和自杀行为的风险也更高。
主体
阿片类药物滥用和自杀行为是适应不良的过程，旨在减轻接受阿片类药物治疗的慢性疼痛患者所经历的负面情绪过度反应、享乐反应减退和情绪调节障碍。在本综述中，我们探讨了情绪调节障碍在慢性疼痛中的作用。然后我们描述了为什么情绪失调的慢性疼痛患者在面对这些负面情绪状态时容易滥用阿片类药物和出现自杀行为。
结论
情绪调节障碍是一个重要且可改变的治疗靶点，有可能减少或预防接受阿片类药物治疗的慢性疼痛患者滥用阿片类药物和自杀行为。
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