Bin Paola, Conti Adelaide, Capasso Emanuele, Fedeli Piergiorgio, Policino Fabio, Casella Claudia, Delbon Paola, Graziano Vincenzo
Department of Surgery, Radiology and Public Health, Public Health and Humanities Section, University of Brescia - Centre of Bioethics Research (with the contribution of IRCCS "S. Giovanni di Dio - Fatebenefratelli"), Italy. P.le Spedali Civili, 1, 25123 Brescia, Italy.
Department of Advanced Biomedical Sciences, University of Naples Federico II, Section of Legal Medicine, Via Sergio Pansini 5, 80131, Naples, Italy.
Open Med (Wars). 2018 Jul 2;13:247-252. doi: 10.1515/med-2018-0038. eCollection 2018.
The aim of this article is to provide an analysis of the main issues related to the application of predictive medicine by analysing the most significant ethical implications. Genetic medicine is indeed a multidisciplinary matter that covers broad contexts, sometimes transversely. Its extreme complexity, coupled with possible perceived repercussions on an individual's life, involves important issues in the ethical, deontological and legal medical field. The aspects related to the execution of genetic testing have to be addressed at different levels, starting with the correct information about the "cognitive" meaning they intend (by forcefully disassociating it from the strange "preventive aspect") to the legal medical issues that can be aroused in the field of forensic pathology, medical responsibility and insurance. There is no doubt that in recent years, from the decoding of the human genome, genetic research has exponentially expanded with an equally exponential increase in its use in clinical practice and the ethical and social evolution of it.
本文旨在通过分析最重要的伦理影响，对与预测医学应用相关的主要问题进行剖析。基因医学确实是一个多学科问题，涵盖广泛的领域，有时甚至是跨领域的。其极端复杂性，再加上可能对个人生活产生的潜在影响，涉及医学伦理、道义和法律领域的重要问题。与基因检测实施相关的各个方面必须在不同层面加以探讨，首先是关于其预期“认知”意义的正确信息（要坚决将其与奇怪的“预防层面”区分开来），直至法医病理学、医疗责任和保险领域可能引发的法律医学问题。毫无疑问，近年来，随着人类基因组的解码，基因研究呈指数级扩展，其在临床实践中的应用以及伦理和社会演变也同样呈指数级增长。
