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由分子定义的非膦锰（I）配合物催化，直接从芳香二胺和醇选择性合成2-取代和1,2-二取代苯并咪唑

Selective Synthesis of 2-Substituted and 1,2-Disubstituted Benzimidazoles Directly from Aromatic Diamines and Alcohols Catalyzed by Molecularly Defined Nonphosphine Manganese(I) Complex.

作者信息

Das Kalicharan, Mondal Avijit, Srimani Dipankar

机构信息

Department of Chemistry , Indian Institute of Technology-Guwahati , Kamrup , Assam 781039 , India.

出版信息

J Org Chem. 2018 Aug 17;83(16):9553-9560. doi: 10.1021/acs.joc.8b01316. Epub 2018 Jul 20.

DOI:10.1021/acs.joc.8b01316
PMID:29993244
Abstract

Herein, we present a selective synthesis of 2-substituted and 1,2-disubstituted benzimidazoles by acceptorless dehydrogenative coupling of aromatic diamine with primary alcohols. The reaction is catalyzed by a phosphine-free tridentate NNS ligand-derived manganese(I) complex.

摘要

在此，我们报道了通过芳族二胺与伯醇的无受体脱氢偶联反应选择性合成2-取代和1,2-二取代苯并咪唑。该反应由一种无膦三齿NNS配体衍生的锰（I）配合物催化。

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