Department of Ophthalmology, University of Padova , Padova , Italy.
Advanced Eye Centre, Post Graduate Institute of Medical Education and Research , Chandigarh , India.
Ocul Immunol Inflamm. 2019;27(7):1049-1051. doi: 10.1080/09273948.2018.1491997. Epub 2018 Jul 11.
: To emphasize the challenge in the diagnosis of granulomatous uveitis, distinguishing clinical, laboratory, and histological features of tuberculosis, sarcoidosis, and borderline entities. : Case report. : A patient coming from tuberculosis endemic area with granulomatous uveitis and generalized lymphadenopathy was first diagnosed with possible intraocular tuberculosis, based on the presence of suggestive clinical signs, caseous central necrosis in lymph node biopsy, and documented exposure to TB. Lack of response to antitubercular therapy together with laboratory test results, radiological and histological findings and negative biopsies for led to the diagnosis of tuberculous-sarcoidosis. : The diagnosis and correct therapeutic strategy of entities that fall in between tuberculosis and sarcoidosis still remains challenging, especially in patients coming from endemic areas.
为强调在诊断肉芽肿性葡萄膜炎时所面临的挑战，需要区分结核病、结节病和交界性疾病的临床、实验室和组织学特征。
病例报告。
一位来自结核病流行地区的患者出现肉芽肿性葡萄膜炎和全身淋巴结病，首先根据提示性临床体征、淋巴结活检中的干酪样中央坏死以及有结核病接触史，诊断为可能的眼内结核。抗结核治疗无效，且实验室检查结果、影像学和组织学发现以及对 的阴性活检结果提示，该患者患有结核-结节病。
对于处于结核病和结节病之间的交界性疾病的诊断和正确的治疗策略仍然具有挑战性，尤其是对于来自流行地区的患者。
