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用于皮肤癌检测的合成超高分辨率毫米波成象技术。

Synthetic Ultra-High-Resolution Millimeter-Wave Imaging for Skin Cancer Detection.

出版信息

IEEE Trans Biomed Eng. 2019 Jan;66(1):61-71. doi: 10.1109/TBME.2018.2837102. Epub 2018 May 17.

Abstract

This work introduces, for the first time, a millimeter-wave imaging system with a "synthetic" ultra-wide imaging bandwidth of 98 GHz to provide the ultra-high resolutions required for early-stage skin cancer detection. The proposed approach consists of splitting the required ultra-wide imaging bandwidth into four sub-bands, and assigning each sub-band to a separate imaging element, i.e., an antenna radiator. Each of the sub-band antennas transmits and receives signals only at its corresponding sub-band. The captured signals are then combined and processed to form the image of the target. For each sub-band, a Vivaldi tapered slot antenna fed with a combination of substrate-integrated waveguide and coplanar waveguide is designed and microfabricated. Design techniques are also provided for the four similarly-shaped sub-band antennas for achieving excellent impedance matches ( S < -10 dB) and nearly constant gains of 10 dBi over the entire 12-110 GHz bandwidth. The design procedure is validated by comparing the simulated results with measurements performed on the fabricated prototypes. Excellent agreements are obtained between simulations and measurements. Finally, the feasibility of detecting early-stage skin tumors in three dimensions is experimentally verified by employing the sub-band antennas in a synthetic ultra-wideband imaging system with a bandwidth of 98 GHz. Two separate setups, each comprising a dispersive skin-mimicking phantom as well as two dispersive spherical tumors, are constructed for imaging experiments. Lateral and axial resolutions of 200 μm are confirmed, and a successful reconstruction of the spherical tumors is achieved in both cases.

摘要

本文首次介绍了一种具有 98GHz“合成”超宽带成像带宽的毫米波成像系统,可为早期皮肤癌检测提供所需的超高分辨率。所提出的方法包括将所需的超宽带成像带宽分为四个子带,并将每个子带分配给单独的成像元件,即天线辐射器。每个子带天线仅在其相应的子带中发送和接收信号。然后将捕获的信号组合并处理以形成目标的图像。对于每个子带,设计并微制造了一种采用基片集成波导和共面波导组合馈电的 Vivaldi 渐变缝隙天线。还提供了用于四个类似形状的子带天线的设计技术,以实现出色的阻抗匹配(S < -10dB)和在整个 12-110GHz 带宽内几乎恒定的 10dBi 增益。通过将仿真结果与在制造原型上进行的测量进行比较,验证了设计过程。仿真和测量之间得到了极好的一致性。最后,通过在带宽为 98GHz 的合成超宽带成像系统中使用子带天线,实验验证了三维检测早期皮肤肿瘤的可行性。构建了两个单独的设置,每个设置都包括一个色散皮肤模拟体以及两个色散球形肿瘤,用于成像实验。确认了 200μm 的横向和轴向分辨率,并在两种情况下均成功重建了球形肿瘤。

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