IEEE J Biomed Health Inform. 2019 Mar;23(2):825-837. doi: 10.1109/JBHI.2018.2823265. Epub 2018 Apr 4.
Sleep disorders are a common health condition that can affect numerous aspects of life. Obstructive sleep apnea is one of the most common disorders and is characterized by a reduction or cessation of airflow during sleep. In many countries, this disorder is usually diagnosed in sleep laboratories, by polysomnography, which is an expensive procedure involving much effort for the patient. Multiple systems have been proposed to address this situation, including performing the examination and analysis in the patient's home, using sensors to detect physiological signals that are automatically analyzed by algorithms. However, the precision of these devices is usually not enough to provide clinical diagnosis. Therefore, the objective of this review is to analyze already existing algorithms that have not been implemented on hardware but have had their performance verified by at least one experiment that aims to detect obstructive sleep apnea to predict trends. The performance of different algorithms and methods for apnea detection through the use of different sensors (pulse oximetry, electrocardiogram, respiration, sound, and combined approaches) has been evaluated. 84 original research articles published from 2003 to 2017 with the potential to be promising diagnostic tools have been selected to cover multiple solutions. This paper could provide valuable information for those researchers who want to carry out a hardware implementation of potential signal processing algorithms.
睡眠障碍是一种常见的健康问题,会影响生活的多个方面。阻塞性睡眠呼吸暂停是最常见的疾病之一,其特征是睡眠期间气流减少或停止。在许多国家,这种疾病通常在睡眠实验室通过多导睡眠图来诊断,这是一种昂贵的程序,患者需要付出很多努力。已经提出了多种系统来解决这种情况,包括在患者家中进行检查和分析,使用传感器来检测生理信号,然后由算法自动进行分析。然而,这些设备的精度通常不足以提供临床诊断。因此,本综述的目的是分析已经存在的算法,但这些算法尚未在硬件上实现,而是已经通过至少一个旨在检测阻塞性睡眠呼吸暂停以预测趋势的实验验证了其性能。评估了通过使用不同传感器(脉搏血氧仪、心电图、呼吸、声音和组合方法)进行睡眠呼吸暂停检测的不同算法和方法的性能。从 2003 年到 2017 年,共选择了 84 篇具有潜在诊断工具的原始研究文章,以涵盖多种解决方案。对于那些希望对潜在信号处理算法进行硬件实现的研究人员来说,本文可以提供有价值的信息。