Department of Chemistry, BITS Pilani, Pilani Campus, Rajasthan 333031, India.
Analyst. 2018 Jul 23;143(15):3741-3748. doi: 10.1039/c8an00349a.
In this article, we tried to redefine the unexplored potential of a benzothiazole type of Schiff-base (OM), which was identified as an AIE-active molecule that exhibits excited-state intramolecular proton transfer (ESIPT). Interestingly, this compound shows ultra-sensitivity and selectivity in the detection of Al(iii) (12 pM; 456 ppt). The OM was capable of pH sensing and was also tested for internalization in cancerous cells for intracellular imaging. Computational modeling was performed and the results were in good agreement with the experimental UV-Vis spectrum and the energy gap obtained in basic and acidic media.
在本文中，我们试图重新定义苯并噻唑型席夫碱（OM）的未探索潜力，该分子被确定为一种具有聚集诱导发光（AIE）活性的分子，表现出激发态分子内质子转移（ESIPT）。有趣的是，该化合物在检测 Al(iii)（12 pM；456 ppt）时具有超高的灵敏度和选择性。OM 能够进行 pH 感测，并已针对癌细胞内的内化进行了细胞内成像测试。进行了计算建模，结果与实验的紫外可见光谱和在碱性和酸性介质中获得的能隙非常吻合。
