Veerman A J, Hogeman P H, van Zantwijk C H, Bezemer P D
Leuk Res. 1985;9(10):1227-9. doi: 10.1016/0145-2126(85)90149-3.
5'-Nucleotidase (5'NT) is an enzyme found on the surface membrane of leukemic cells with the c-ALL phenotype. We studied 79 children with acute lymphoblastic leukemia (ALL). Thirty six of them had the c-ALL phenotype. Within this c-ALL group, ten had 5'-NT positive leukemic cells. Clinical data were available in 33 c-ALL cases. Sex, age and initial white blood cell count were comparable between 5'NT positive and 5'NT negative c-ALL cases. In the 5'NT positive group the probability of complete continuous remission was significantly lower than in the 5'NT negative group (p less than 0.05).
5'-核苷酸酶（5'NT）是一种在具有普通型急性淋巴细胞白血病（c-ALL）表型的白血病细胞膜表面发现的酶。我们研究了79名急性淋巴细胞白血病（ALL）患儿。其中36名具有c-ALL表型。在这个c-ALL组中，10名患儿的白血病细胞5'-NT呈阳性。33例c-ALL病例有临床数据。5'-NT阳性和5'-NT阴性的c-ALL病例在性别、年龄和初始白细胞计数方面具有可比性。在5'-NT阳性组中，完全持续缓解的概率显著低于5'-NT阴性组（p<0.05）。
