Outcome measures of disease activity for rare autoimmune rheumatic diseases.

作者信息

Jones Alexis, Cotton Alice, Guinto Jesusa, Wilton James, Ciurtin Coziana

机构信息

Senior Clinical Research Fellow, Department of Rheumatology, University College London Hospital NHS Trust, London NW1 2PQ.

Clinical Research Nurse, Department of Rheumatology, University College London Hospital NHS Trust, London.

出版信息

Br J Hosp Med (Lond). 2018 Jul 2;79(7):396-401. doi: 10.12968/hmed.2018.79.7.396.

DOI:10.12968/hmed.2018.79.7.396

PMID:29995544

Abstract

Systemic lupus erythematosus, scleroderma, myositis and Sjögren's syndrome are rare, complex, multi-systemic rheumatic diseases associated with significant morbidity and mortality. Thorough assessments of disease activity are required to guide clinical management and assess response to new therapies in clinical trials. This article reviews the commonly used outcome measures to assess this group of diseases and discusses the limitations of their use.

摘要