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异位错构瘤性胸腺瘤(双表型鳃瘤):一例病例报告及文献复习

Ectopic hamartomatous thymoma (biphenotypic branchioma): A case report and review of the literature.

作者信息

Cui Wenwen, Li Dongliang, Liu Yang, Pang Yuwen, Zhang Liang, Liu Chunxia, Li Feng

机构信息

Department of Pathology and The Key Laboratories for Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Shihezi, Xinjiang, China Department of Pathology, Beijing Chaoyang Hospital, Capital Medical University, Beijing Lu'an People's Hospital. Lu'an Affiliated Hospital of Anhui Medical University, Lu'an, Anhui Department of Pathology, Binzhou People's Hospital, Shandong Province, Binzhou, China.

出版信息

Medicine (Baltimore). 2018 Jul;97(28):e11459. doi: 10.1097/MD.0000000000011459.

DOI:10.1097/MD.0000000000011459
PMID:29995801
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6076095/
Abstract

RATIONALE

Ectopic hamartomatous thymoma is a very rare soft tissue neoplasm that commonly occurs in the lower neck of adult men.

PATIENT CONCERNS

A 32-year-old male presented 1-year history of the tumor lying in left supraclavicular fossa.

DIAGNOSES

Initial consideration of ultrasound and computed tomography was lipoma. After the operation, the pathologist diagnosed it as Ectopic Hamartomatous Thymoma.

INTERVENTIONS

A complete resection was performed.

OUTCOMES

To date, the patient had no evidence of metastasis or recurrence for 26 months after the operation.

LESSONS

Ectopic hamartomatous thymoma is rare. The mastery of the clinical and pathological features of the disease will contribute to the rapid diagnosis and treatment of the disease. In addition, it can be considered to update the name to "biphenotypic branchioma" in order to avoid conceptual confusion.

摘要

理论依据

异位错构瘤性胸腺瘤是一种非常罕见的软组织肿瘤,常见于成年男性的下颈部。

患者情况

一名32岁男性,有1年肿瘤位于左锁骨上窝的病史。

诊断

最初超声和计算机断层扫描考虑为脂肪瘤。术后,病理学家诊断为异位错构瘤性胸腺瘤。

干预措施

进行了完整切除。

结果

迄今为止,患者术后26个月无转移或复发迹象。

经验教训

异位错构瘤性胸腺瘤罕见。掌握该疾病的临床和病理特征将有助于疾病的快速诊断和治疗。此外,为避免概念混淆,可考虑将其名称更新为“双表型鳃瘤”。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15a7/6076095/6d9e5f3b5a9b/medi-97-e11459-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15a7/6076095/593d7c31c863/medi-97-e11459-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15a7/6076095/b68bb027981d/medi-97-e11459-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15a7/6076095/08edbcde8cde/medi-97-e11459-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15a7/6076095/6d9e5f3b5a9b/medi-97-e11459-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15a7/6076095/593d7c31c863/medi-97-e11459-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15a7/6076095/b68bb027981d/medi-97-e11459-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15a7/6076095/08edbcde8cde/medi-97-e11459-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15a7/6076095/6d9e5f3b5a9b/medi-97-e11459-g004.jpg

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本文引用的文献

1
Ectopic Hamartomatous Thymoma: A Review Of The Literature With Report Of New Cases And Proposal Of A New Name: Biphenotypic Branchioma.异位错构瘤性胸腺瘤:文献综述及新病例报告与新命名提议:双表型鳃瘤
Head Neck Pathol. 2018 Jun;12(2):202-209. doi: 10.1007/s12105-017-0854-6. Epub 2017 Sep 6.
2
Two Cases of Ectopic Hamartomatous Thymoma Masquerading as Sarcoma.两例伪装成肉瘤的异位错构瘤性胸腺瘤
Case Rep Otolaryngol. 2017;2017:1672919. doi: 10.1155/2017/1672919. Epub 2017 Jan 10.
3
Ectopic Hamartomatous Thymoma-New Insights Into a Challenging Entity: A Clinicopathologic and Immunohistochemical Study of 9 Cases.
异位错构瘤性胸腺瘤——对一个具有挑战性实体的新认识:9例临床病理及免疫组化研究
Am J Surg Pathol. 2016 Nov;40(11):1571-1576. doi: 10.1097/PAS.0000000000000699.
4
Benign anlage tumour: a very unusual neck mass.良性胚基肿瘤:一种非常罕见的颈部肿块。
BMJ Case Rep. 2016 May 18;2016:bcr2016215789. doi: 10.1136/bcr-2016-215789.
5
A Rare Presternal Soft Tissue Tumor: Ectopic Hamartomatous Thymoma (Branchial Anlage Mixed Tumor).一种罕见的胸骨前软组织肿瘤:异位错构瘤性胸腺瘤(鳃原基混合瘤)。
Acta Chir Belg. 2015 Nov-Dec;115(6):418-22. doi: 10.1080/00015458.2015.11681144.
6
Ectopic hamartomatous thymoma: report of a case and review of literature.异位错构瘤性胸腺瘤:一例报告并文献复习
Int J Clin Exp Pathol. 2015 Sep 1;8(9):11776-84. eCollection 2015.
7
An ectopic hamartomatous thymoma compressing left jugular vein.一例异位错构瘤性胸腺瘤压迫左颈静脉。
Niger J Clin Pract. 2014 Nov-Dec;17(6):814-6. doi: 10.4103/1119-3077.144407.
8
An ectopic hamartomatous thymoma.异位错构瘤性胸腺瘤。
Auris Nasus Larynx. 2012 Feb;39(1):110-3. doi: 10.1016/j.anl.2011.07.016. Epub 2011 Sep 1.
9
Ectopic hamartomatous thymoma--a truly rare neoplasm: report of a case.异位错构性胸腺瘤——一种真正罕见的肿瘤:病例报告。
Surg Today. 2010;40(2):146-9. doi: 10.1007/s00595-009-4019-4. Epub 2010 Jan 28.
10
Ectopic hamartomatous thymoma: a case demonstrating skin adnexal differentiation with positivity for epithelial membrane antigen, androgen receptors, and BRST-2 by immunohistochemistry.异位错构瘤性胸腺瘤:1例通过免疫组化显示皮肤附属器分化且上皮膜抗原、雄激素受体和BRST-2呈阳性的病例。
Hum Pathol. 2007 Jul;38(7):1092-1095. doi: 10.1016/j.humpath.2007.01.029.