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青少年特发性脊柱侧凸主胸弯Cobb角分布的回顾性对照临床研究

A retrospective controlled clinical study of Cobb angle distribution of the main thoracic curve in adolescent idiopathic scoliosis.

作者信息

Zhao Jian, Fan Jianping, Chen Yuanyuan, Yang Changwei, Li Gengwu, Li Ming

机构信息

Department of Orthopedics, Changhai Hospital of the Second Military Medical University, Shanghai Department of Orthopedics of Jinling Hospital, Nanjing University, School of Medicine, Nanjing, Jiangsu Department of Orthopedics, Handan No. 285 Hospital of the Chinese People's Liberation Army, Handan, Hebei Department of Laboratory Medicine, Changhai Hospital, Shanghai Panzhihua Central Hospital, Panzhihua, China.

出版信息

Medicine (Baltimore). 2018 Jul;97(28):e11473. doi: 10.1097/MD.0000000000011473.

Abstract

To compare the characteristics of Cobb angle distribution of the main thoracic curve (MTC) in patients with Lenke 1 adolescent idiopathic scoliosis (AIS) and differences in fulcrum-bending flexibility, correction rate, and correction index between different segments.Included in this study were 40 consecutive patients with Lenke 1 AIS who received posterior correction and fusion with pedicle screws. Cobb angle based on the proximal (T5-T7 or T6-T8), apical (T7-T9 or T8-T10), and distal (T9-T11 or T10-T12) segments in the fulcrum-bending position was measured before and after surgery. The flexibility ([Cobb angle of each segment - residual Cobb angle on fulcrum bending]/Cobb angle of each segment × 100%), correction rate ([Cobb angle of each segment - postoperative residual Cobb angle]/Cobb angle of each segment × 100%]), and correction index (correction rate of each segment/preoperative flexibility of each segment) in different segments were calculated. Comparative analyses were conducted by variance analysis.The mean age before surgery, Cobb angle, Risser sign, and follow-up time were 14.15 ± 2.13 years, 51.17 ± 10.72°, 2.78 ± 1.73, and 43.75 ± 9.82 months, respectively. MTC Cobb angle of the proximal segments was similar to that of the distal ones (12.88 ± 4.81 vs 12.85 ± 5.00) versus 25.45 ± 5.90 in the middle segments (P < .001). The flexibility was higher in the distal segments than that in the proximal or apical segments (66.43 ± 0.22% vs 43.78 ± 0.20% or 32.55 ± 0.17%, P < .001). One week after surgery, the correction rate in these 3 segments was 69.55 ± 0.1%, 66.25 ± 0.17%, and 75.28 ± 0.16 (P = .067), and the correction index was 2.15 ± 1.78, 3.16 ± 3.60, and 1.53 ± 1.93 (P = .019); the correction rate during the 3-year follow-up period was 68.06 ± 0.19%, 69.98 ± 0.15%, and 73.29 ± 0.17 (P = .212); and the correction index was 2.12 ± 1.78, 3.20 ± 3.54, and 1.49 ± 1.93 (P = .012), respectively.The proximal, apical, and distal segments in Lenke 1 AIS accounted for about 25%, 50%, and 25% of MTC Cobb angle, respectively. The distal segments were found to be most flexible and the apical segments most rigid. The correction rate was similar between the proximal, apical, and distal segments, and the correction index in the apical segments was higher than that in the proximal and distal segments.

摘要

比较Lenke 1型青少年特发性脊柱侧凸(AIS)患者主胸弯(MTC)的Cobb角分布特征以及不同节段在支点弯曲灵活性、矫正率和矫正指数方面的差异。本研究纳入40例连续接受后路矫正及椎弓根螺钉融合术的Lenke 1型AIS患者。在支点弯曲位测量手术前后基于近端(T5 - T7或T6 - T8)、顶椎(T7 - T9或T8 - T10)和远端(T9 - T11或T10 - T12)节段的Cobb角。计算不同节段的灵活性([各节段Cobb角 - 支点弯曲时残留Cobb角]/各节段Cobb角×100%)、矫正率([各节段Cobb角 - 术后残留Cobb角]/各节段Cobb角×100%)和矫正指数(各节段矫正率/各节段术前灵活性)。采用方差分析进行比较分析。手术前的平均年龄、Cobb角、Risser征和随访时间分别为14.15±2.13岁、51.17±10.72°、2.78±1.73和43.75±9.82个月。近端节段的MTC Cobb角与远端节段相似(12.88±4.81对12.85±5.00),而中段为25.45±5.90(P<0.001)。远端节段的灵活性高于近端或顶椎节段(66.43±0.22%对43.78±0.20%或32.55±0.17%,P<0.001)。术后1周,这3个节段的矫正率分别为69.55±0.1%、66.25±0.17%和75.28±0.16(P = 0.067),矫正指数分别为2.15±1.78、3.16±3.60和1.53±1.93(P = 0.019);3年随访期的矫正率分别为68.06±0.19%、69.98±0.15%和73.29±0.17(P = 0.212);矫正指数分别为2.12±1.78、3.20±3.54和1.49±1.93(P = 0.012)。Lenke 1型AIS的近端、顶椎和远端节段分别约占MTC Cobb角的25%、50%和25%。发现远端节段最灵活,顶椎节段最僵硬。近端、顶椎和远端节段的矫正率相似,顶椎节段的矫正指数高于近端和远端节段。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93ae/6076177/c25bd5a43e6e/medi-97-e11473-g001.jpg

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