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一只患有化脓性乳腺炎的山羊因感染性心内膜炎继发二尖瓣亲吻性赘生物和获得性主动脉瓣狭窄

Mitral Kissing Vegetation and Acquired Aortic Valve Stenosis Secondary to Infectious Endocarditis in a Goat with Suppurative Mastitis.

作者信息

Watson Antonio, Sookram Vade, Driscoll Marc, Morris Michael, Suepaul Rod, López-Alvarez Jordi, Corradini Ignacio

机构信息

Department of Clinical Veterinary Sciences, School of Veterinary Medicine, The University of the West Indies, EWMSC, Mt. Hope, Trinidad and Tobago.

School of Veterinary Medicine, The University of the West Indies, EWMSC, Mt. Hope, Trinidad and Tobago.

出版信息

Vet Sci. 2018 Jul 10;5(3):64. doi: 10.3390/vetsci5030064.

Abstract

A six-year-old female goat was presented to the veterinary teaching hospital of the University of the West Indies with a history of progressive hind-limb paresis lasting two weeks. The doe developed a grade 6/6 holosystolic murmur during hospitalisation. Echocardiography revealed vegetative growths attached to cusps of the mitral and aortic valves. There was an accelerated aortic flow at 2.9 m/s and aortic insufficiency. The aortic vegetation was prolapsing into the left ventricle during diastole, causing it to contact the septal mitral valve leaflet. A diagnosis of mitral and aortic vegetative endocarditis, with a mitral kissing vegetation and mild aortic stenosis, was reached. The patient was placed on broad-spectrum antimicrobials. A short-term follow-up showed no resolution of clinical signs, and the animal eventually died. Post-mortem examination showed severe vegetative, fibrino-necrotic, aortic and mitral valve lesions. The goat also had a severe fibrino-suppurative mastitis. Histopathology confirmed the lesions to be vegetative endocarditis.

摘要

一只六岁的雌性山羊被送到西印度群岛大学兽医教学医院,有持续两周的进行性后肢轻瘫病史。这只母羊在住院期间出现了6/6级全收缩期杂音。超声心动图显示赘生物附着在二尖瓣和主动脉瓣叶上。主动脉血流速度为2.9米/秒,有主动脉瓣关闭不全,主动脉血流加速。主动脉赘生物在舒张期脱垂至左心室,使其与二尖瓣隔叶接触。诊断为二尖瓣和主动脉瓣赘生性心内膜炎,伴有二尖瓣吻合赘生物和轻度主动脉瓣狭窄。患者接受了广谱抗菌药物治疗。短期随访显示临床症状未缓解,该动物最终死亡。尸检显示主动脉和二尖瓣有严重的赘生性、纤维蛋白坏死性病变。这只山羊还患有严重的纤维蛋白化脓性乳腺炎。组织病理学证实病变为赘生性心内膜炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04e2/6164705/5258c8b04800/vetsci-05-00064-g001.jpg

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