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局部和靶向递送达非甾体抗炎药治疗炎症:综述。

Localized and targeted delivery of NSAIDs for treatment of inflammation: A review.

机构信息

Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA.

出版信息

Exp Biol Med (Maywood). 2019 Apr;244(6):433-444. doi: 10.1177/1535370218787770. Epub 2018 Jul 12.

DOI:10.1177/1535370218787770
PMID:29996674
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6546999/
Abstract

This work provides an overview of research currently being done exploring potential drug delivery device strategies for NSAIDs as an alternative to systemic delivery. Commentary on this field is made in an attempt to aid future experimental design, enabling researchers to determine the drugs and delivery vehicles which are most advantageous for them to pursue, as well as suggestions to standardize the reporting of such future research.

摘要

这项工作概述了目前正在研究的 NSAIDs 潜在药物输送装置策略,作为全身给药的替代方法。对该领域的评论旨在帮助未来的实验设计,使研究人员能够确定最有利于他们追求的药物和输送载体,并提出建议,使未来的研究报告标准化。

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本文引用的文献

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Solid lipid nanoparticles for the controlled delivery of poorly water soluble non-steroidal anti-inflammatory drugs.固体脂质纳米粒用于控制传递水中溶解度差的非甾体抗炎药物。
Ultrason Sonochem. 2018 Jan;40(Pt A):686-696. doi: 10.1016/j.ultsonch.2017.08.018. Epub 2017 Aug 19.
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Nanofibrillar cellulose hydrogels and reconstructed hydrogels as matrices for controlled drug release.纳米原纤纤维素水凝胶和重建水凝胶作为控制药物释放的基质。
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Novel poly(ε-caprolactone)/gelatin wound dressings prepared by emulsion electrospinning with controlled release capacity of Ketoprofen anti-inflammatory drug.通过乳液静电纺丝制备的具有酮洛芬抗炎药物控释能力的新型聚(ε-己内酯)/明胶伤口敷料。
Mater Sci Eng C Mater Biol Appl. 2017 Dec 1;81:459-468. doi: 10.1016/j.msec.2017.08.025. Epub 2017 Aug 10.
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